17
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: not found
      • Article: not found

      The impact of transposable elements in adaptive evolution

      1 , 2
      Molecular Ecology
      Wiley

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The growing knowledge about the influence of transposable elements (TEs) on (a) long-term genome and transcriptome evolution; (b) genomic, transcriptomic and epigenetic variation within populations; and (c) patterns of somatic genetic differences in individuals continues to spur the interest of evolutionary biologists in the role of TEs in adaptive evolution. As TEs can trigger a broad range of molecular variation in a population with potentially severe fitness and phenotypic consequences for individuals, different mechanisms evolved to keep TE activity in check, allowing for a dynamic interplay between the host, its TEs and the environment in evolution. Here, we review evidence for adaptive phenotypic changes associated with TEs and the basic molecular mechanisms by which the underlying genetic changes arise: (a) domestication, (b) exaptation, (c) host gene regulation, (d) TE-mediated formation of intronless gene copies-so-called retrogenes and (e) overall increased genome plasticity. Furthermore, we review and discuss how the stress-dependent incapacitation of defence mechanisms against the activity of TEs might facilitate adaptive responses to environmental challenges and how such mechanisms might be particularly relevant in species frequently facing novel environments, such as invasive, pathogenic or parasitic species.

          Related collections

          Most cited references116

          • Record: found
          • Abstract: not found
          • Article: not found

          Evolutionary genetics of invasive species

            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            The HSP90 chaperone machinery

            The heat shock protein 90 (HSP90) chaperone machinery is a key regulator of proteostasis. Recent progress has shed light on the interactions of HSP90 with its clients and co-chaperones, and on their functional implications. This opens up new avenues for the development of drugs that target HSP90, which could be valuable for the treatment of cancers and protein-misfolding diseases.
              Bookmark
              • Record: found
              • Abstract: not found
              • Article: not found

              The heat-shock response.

                Bookmark

                Author and article information

                Journal
                Molecular Ecology
                Mol Ecol
                Wiley
                09621083
                August 04 2018
                Affiliations
                [1 ]Institute for Evolution and Biodiversity (IEB); University of Münster; Münster Germany
                [2 ]Institute of Experimental Pathology; University of Münster; Münster Germany
                Article
                10.1111/mec.14794
                30003608
                3a81a711-11a8-4696-8f27-f896a8debf5c
                © 2018

                http://doi.wiley.com/10.1002/tdm_license_1.1

                http://onlinelibrary.wiley.com/termsAndConditions#vor

                History

                Comments

                Comment on this article