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      Application of Biodegradable and Biocompatible Nanocomposites in Electronics: Current Status and Future Directions

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          Abstract

          With the continuous increase in the production of electronic devices, large amounts of electronic waste (E-waste) are routinely being discarded into the environment. This causes serious environmental and ecological problems because of the non-degradable polymers, released hazardous chemicals, and toxic heavy metals. The appearance of biodegradable polymers, which can be degraded or dissolved into the surrounding environment with no pollution, is promising for effectively relieving the environmental burden. Additionally, biodegradable polymers are usually biocompatible, which enables electronics to be used in implantable biomedical applications. However, for some specific application requirements, such as flexibility, electric conductivity, dielectric property, gas and water vapor barrier, most biodegradable polymers are inadequate. Recent research has focused on the preparation of nanocomposites by incorporating nanofillers into biopolymers, so as to endow them with functional characteristics, while simultaneously maintaining effective biodegradability and biocompatibility. As such, bionanocomposites have broad application prospects in electronic devices. In this paper, emergent biodegradable and biocompatible polymers used as insulators or (semi)conductors are first reviewed, followed by biodegradable and biocompatible nanocomposites applied in electronics as substrates, (semi)conductors and dielectrics, as well as electronic packaging, which is highlighted with specific examples. To finish, future directions of the biodegradable and biocompatible nanocomposites, as well as the challenges, that must be overcome are discussed.

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          Chemical sensors based on amplifying fluorescent conjugated polymers.

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            Dissolvable films of silk fibroin for ultrathin conformal bio-integrated electronics.

            Electronics that are capable of intimate, non-invasive integration with the soft, curvilinear surfaces of biological tissues offer important opportunities for diagnosing and treating disease and for improving brain/machine interfaces. This article describes a material strategy for a type of bio-interfaced system that relies on ultrathin electronics supported by bioresorbable substrates of silk fibroin. Mounting such devices on tissue and then allowing the silk to dissolve and resorb initiates a spontaneous, conformal wrapping process driven by capillary forces at the biotic/abiotic interface. Specialized mesh designs and ultrathin forms for the electronics ensure minimal stresses on the tissue and highly conformal coverage, even for complex curvilinear surfaces, as confirmed by experimental and theoretical studies. In vivo, neural mapping experiments on feline animal models illustrate one mode of use for this class of technology. These concepts provide new capabilities for implantable and surgical devices.
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              Processing technologies for poly(lactic acid)

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                Author and article information

                Journal
                Nanomaterials (Basel)
                Nanomaterials (Basel)
                nanomaterials
                Nanomaterials
                MDPI
                2079-4991
                29 June 2019
                July 2019
                : 9
                : 7
                : 950
                Affiliations
                [1 ]Academic Division of Engineering, Qingdao University of Science & Technology, Qingdao 266061, China
                [2 ]College of Mechanical and Electrical Engineering, Beijing University of Chemical Technology, Beijing 100029, China
                [3 ]College of Electromechanical Engineering, Qingdao University of Science & Technology, Qingdao 266061, China
                [4 ]College of Sino-German Science and Technology, Qingdao University of Science & Technology, Qingdao 266061, China
                [5 ]College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA
                [6 ]Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
                Author notes
                [* ]Correspondence: Zhaogang.Yang@ 123456UTSouthwestern.edu (Z.Y.); sunjingyao@ 123456mail.buct.edu.cn (J.S.); wcsmta@ 123456qust.edu.cn (C.W.); Tel.: +1-214-645-6873 (Z.Y.); +86-10-6443-5015 (J.S.); +86-136-0896-6169 (C.W.)
                [†]

                These authors contributed equally to this work.

                Article
                nanomaterials-09-00950
                10.3390/nano9070950
                6669760
                31261962
                3b92ad8e-a476-45a6-81de-716ce733615e
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 15 May 2019
                : 24 June 2019
                Categories
                Review

                biodegradable,biocompatible,electronics,nanocomposites
                biodegradable, biocompatible, electronics, nanocomposites

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