Early propranolol after traumatic brain injury is associated with lower mortality.

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Abstract

β-Adrenergic receptor blockers (BBs) administered after trauma blunt the cascade of immune and inflammatory changes associated with injury. BBs are associated with improved outcomes after traumatic brain injury (TBI). Propranolol may be an ideal BB because of its nonselective inhibition and ability to cross the blood-brain barrier. We determined if early administration of propranolol after TBI is associated with lower mortality.

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Journal

Journal ID (iso-abbrev): J Trauma Acute Care Surg

Title: The journal of trauma and acute care surgery

ISSN (Electronic): 2163-0763

ISSN (Print): 2163-0755

Publication date (Electronic): Apr 2016

Volume: 80

Issue: 4

Affiliations

[1 ] From the Division of Trauma and Critical Care, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California.

Article

DOI: 10.1097/TA.0000000000000959

PubMed ID: 26808028

SO-VID: 43876e31-aac6-4d89-812f-4f384b844db3

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