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      Early propranolol after traumatic brain injury is associated with lower mortality.

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          Abstract

          β-Adrenergic receptor blockers (BBs) administered after trauma blunt the cascade of immune and inflammatory changes associated with injury. BBs are associated with improved outcomes after traumatic brain injury (TBI). Propranolol may be an ideal BB because of its nonselective inhibition and ability to cross the blood-brain barrier. We determined if early administration of propranolol after TBI is associated with lower mortality.

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          Author and article information

          Journal
          J Trauma Acute Care Surg
          The journal of trauma and acute care surgery
          2163-0763
          2163-0755
          Apr 2016
          : 80
          : 4
          Affiliations
          [1 ] From the Division of Trauma and Critical Care, Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, California.
          Article
          10.1097/TA.0000000000000959
          26808028

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