Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, USA
)
ISSN
(Electronic):
1932-6203
Publication date Collection: 2012
Publication date
(Electronic):
16
November
2012
Volume: 7
Issue: 11
Electronic Location Identifier: e49452
Affiliations
[1
]UCSF Diabetes Center and Department of Cell and Tissue Biology, University of California
San Francisco, San Francisco, California, United States of America
[2
]Department of Radiology, Childrens Hospital Los Angeles, University of Southern California,
Los Angeles, California, United States of America
[3
]Department of Pathology, Childrens Hospital Los Angeles, University of Southern California,
Los Angeles, California, United States of America
Graduate School of Medicine, the University of Tokyo, Japan
Author notes
Competing Interests: Regarding the funding from a commercial source (Asubio Pharma Co.), the authors declare
that they have no conflicts of interest, including employment, consultancy, patents,
products in development or marketed products. This does not alter the authors’ adherence
to all the PLOS ONE policies on sharing data and materials.
Conceived and designed the experiments: VG SK. Performed the experiments: LZS KS HO
DWS ET LR HH LW ZP SK. Analyzed the data: LZS KS HO HH VG SK. Contributed reagents/materials/analysis
tools: HH LW ZP VG. Wrote the paper: LZS KS HO SK.
Article
Publisher ID:
PONE-D-12-17813
DOI: 10.1371/journal.pone.0049452
PMC ID: 3500293
PubMed ID: 23166672
SO-VID: 5091c228-bb23-4c7f-bb9f-d937ce4ee6f8
Copyright statement:
Copyright @
2012
License:
This is an open-access article distributed under the terms of the Creative Commons
Attribution License, which permits unrestricted use, distribution, and reproduction
in any medium, provided the original author and source are credited.
This work was supported by grants from the National Institutes of Health to SK (R00DK087853)
and to VG (R21DK090778 and K25DK087931). This work was also supported by grants from
UCSF Program for Breakthrough Biomedical Research (PBBR) and from Asubio Pharma Co.
to SK. LZS is supported by CIRM Bridges fellowship (TB1-01197). HO is supported by
Manpei Suzuki Diabetes Foundation. The funders had no role in study design, data collection
and analysis, decision to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology
Subject:
Anatomy and Physiology
Subject:
Endocrine System
Subject:
Diabetic Endocrinology
Subject:
Endocrine Physiology
Subject:
Physiological Processes
Subject:
Energy Metabolism
Subject:
Biochemistry
Subject:
Lipids
Subject:
Fats
Subject:
Lipid Metabolism
Subject:
Metabolism
Subject:
Lipid Metabolism
Subject:
Metabolic Pathways
Subject:
Developmental Biology
Subject:
Cell Fate Determination
Subject:
Model Organisms
Subject:
Animal Models
Subject:
Mouse
Subject:
Medicine
Subject:
Anatomy and Physiology
Subject:
Endocrine System
Subject:
Diabetic Endocrinology
Subject:
Endocrine Physiology
Subject:
Physiological Processes
Subject:
Energy Metabolism
Subject:
Homeostasis
Subject:
Endocrinology
Subject:
Diabetic Endocrinology
Subject:
Diabetes Mellitus Type 2
Subject:
Endocrine Physiology
Subject:
Hormones
Subject:
Metabolic Disorders
Subject:
Nutrition
Subject:
Obesity