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      Forschung im Bereich der Laserakupunktur und Lasermedizin Translated title: Innovatives Pilotprojekt mit Peking in COVID-19-Pandemie-Zeiten

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          Abstract

          Dieses innovative Projekt im Rahmen einer erfolgreichen chinesisch-österreichischen Kooperation zur Hightech-Akupunktur zwischen der Pekinger Universität für Chinesische Medizin und der Medizinischen Universität Graz befasst sich mit der Förderung eines neuen Forschungsfeldes mit den Bezeichnungen Laserakupunktur und Lasermedizin. Laserakupunktur ist definiert als „Photonische Stimulation von Akupunkturpunkten und Bereichen, um therapeutische Wirkungen zu initiieren, die denen der Nadelakupunktur und verwandten Therapien ähnlich sind, zusammen mit den Vorteilen der PhotoBio-Modulation (PBM)“. Die Praxis der Laserakupunktur scheint in China noch in den Kinderschuhen zu stecken. Daher wird gemeinsam mit dem österreichischen Projektpartner in China, dem Dekan der Pekinger Universität für Chinesische Medizin, eine qualitativ hochwertige Einführung in die Thematik in Peking durchgeführt. Dazu ist bereits vor kurzem der erste lehrbuchspezifische Bericht über Laserakupunktur und innovative Lasermedizin in chinesischer Sprache erschienen. Im Rahmen von Meinungsführer- und Studentendiskussionen und Vorträgen soll das wichtige neue Forschungsfeld evidenzbasiert wissenschaftlich aufgrund der Pandemie „online“ beworben werden. Dies bietet die Chance, bestehende Kooperationen zu intensivieren und gegebenenfalls nach Zeiten der COVID-19-Pandemie neue gemeinsame Forschungsaktivitäten zu starten.

          Translated abstract

          This innovative project within a successful Sino-Austrian cooperation on high-tech acupuncture between Beijing University of Chinese Medicine and Medical University of Graz deals with the promotion of a new research field entitled laser acupuncture and laser medicine. Laser acupuncture is defined as “Photonic stimulation of acupuncture points and areas to initiate therapeutic effects similar to that of needle acupuncture and related therapies together with the benefits of PhotoBioModulation (PBM)“. The practice of laser acupuncture in China still seems to be in its infancy. Therefore, together with the Austrian project partner in China, the dean of the of the Beijing University of Chinese Medicine, a high-quality introduction into the topic is performed in Beijing. For this purpose, the first textbook report about laser acupuncture and innovative laser medicine in Chinese language has been released already recently. Within opinion leader and student discussions and lectures the important new research field should be promoted in an evidencebased scientific new ‘online’ way due to pandemic. This offers the opportunity to intensify existing cooperation and to start possibly new joint research activities after COVID-19 pandemic times.

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          Most cited references26

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          Curcumin and Photobiomodulation in Chronic Viral Hepatitis and Hepatocellular Carcinoma

          Immune modulation is a very modern medical field for targeting viral infections. In the race to develop the best immune modulator against viruses, curcumin, as a natural product, is inexpensive, without side effects, and can stimulate very well certain areas of the human immune system. As a bright yellow component of turmeric spice, curcumin has been the subject of thousands of scientific and clinical studies in recent decades to prove its powerful antioxidant properties and anticancer effects. Curcumin has been shown to influence inter- and intracellular signaling pathways, with direct effects on gene expression of the antioxidant proteins and those that regulate the immunity. Experimental studies have shown that curcumin modulates several enzyme systems, reduces nitrosative stress, increases the antioxidant capacity, and decreases the lipid peroxidation, protecting against fatty liver pathogenesis and fibrotic changes. Hepatitis B virus (HBV) affects millions of people worldwide, having sometimes a dramatic evolution to chronic aggressive infection, cirrhosis, and hepatocellular carcinoma. All up-to-date treatments are limited, there is still a gap in the scientific knowledge, and a sterilization cure may not yet be possible with the removal of both covalently closed circular DNA (cccDNA) and the embedded HBV DNA. With a maximum light absorption at 420 nm, the cytotoxicity of curcumin as photosensitizer could be expanded by the intravenous blue laser blood irradiation (IVBLBI) or photobiomodulation in patients with chronic hepatitis B infection, Hepatitis B e-antigen (HBeAg)-positive, noncirrhotic, but nonresponsive to classical therapy. Photobiomodulation increases DNA repair by the biosynthesis of complex molecules with antioxidant properties, the outset of repairing enzyme systems and new phospholipids for regenerating the cell membranes. UltraBioavailable Curcumin and blue laser photobiomodulation could suppress the virus and control better the disease by reducing inflammation/fibrosis and stopping the progression of chronic hepatitis, reversing fibrosis, and diminishing the progression of cirrhosis, and decreasing the incidence of hepatocellular carcinoma. Photodynamic therapy with blue light and curcumin opens new avenues for the effective prevention and cure of chronic liver infections and hepatocellular carcinoma. Blue laser light and UltraBioavailable Curcumin could be a new valuable alternative for medical applications in chronic B viral hepatitis and hepatocarcinoma, saving millions of lives.
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            Differential brain effects of laser and needle acupuncture at LR8 using functional MRI

            Objective While needle acupuncture is a well-accepted technique, laser acupuncture is being increasingly used in clinical practice. The differential effects of the two techniques are of interest. We examine this in relation to brain effects of activation of LR8, a putative acupuncture point for depression, using functional MRI (fMRI). Methods Sixteen healthy participants were randomised to receive low intensity laser acupuncture to LR8 on one side and needle acupuncture to the contralateral LR8. Stimulation was in an on-off block design and brain patterns were recorded under fMRI. Results Significant activation occurred in the left precuneus during laser acupuncture compared with needle acupuncture and significant activation occurred in the left precentral gyrus during needle acupuncture compared with laser acupuncture. Conclusions Laser and needle acupuncture at LR8 in healthy participants produced different brain patterns. Laser acupuncture activated the precuneus relevant to mood in the posterior default mode network while needle acupuncture activated the parietal cortical region associated with the primary motor cortex. Further investigations are warranted to evaluate the clinical relevance of these effects.
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              Definition of Laser Acupuncture and All Kinds of Photo Acupuncture

              This editorial contains a general definition of laser acupuncture and all kinds of photo acupuncture accepted by the World Association for photobiomoduLation Therapy (WALT).
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                Author and article information

                Contributors
                gerhard.litscher@medunigraz.at
                Journal
                Akupunkt Aurikulomed
                Akupunktur & Aurikulomedizin
                Springer Medizin (Heidelberg )
                2192-9319
                2196-6400
                20 June 2022
                2022
                : 48
                : 2
                : 15-20
                Affiliations
                GRID grid.11598.34, ISNI 0000 0000 8988 2476, Chairman des TCM Forschungszentrums Graz, Medizinische Universität Graz, ; Auenbruggerplatz 39, EG19, 8036 Graz, Österreich
                Article
                5776
                10.1007/s15009-022-5776-z
                9593993
                618bb972-c24f-49a3-a666-c54875e60c83
                © Springer ^Medizin 2022

                This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.

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                © Springer Medizin 2022

                laserakupunktur,hightech-akupunktur,chinesischösterreichische kooperation,evidenzbasierte komplementärmedizin,innovative lasermedizin,laser acupuncture,high-tech acupuncture,sino-austrian cooperation,evidence-based complementary medicine,innovative laser medicine

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