Contributors
Ricardo Costeira: Role: Formal analysisRole: InvestigationRole: MethodologyRole: Writing – original
draftRole: Writing – review & editing
Karla A. Lee:
ORCID: https://orcid.org/0000-0001-5904-5586
Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – original
draftRole: Writing – review & editing
Benjamin Murray: Role: Data curationRole: Writing – review & editing
Colette Christiansen: Role: Formal analysisRole: Writing – review & editing
Juan Castillo-Fernandez: Role: Data curationRole: Writing – review & editing
Mary Ni Lochlainn: Role: InvestigationRole: Writing – review & editing
Joan Capdevila Pujol: Role: ResourcesRole: Software
Heather Macfarlane: Role: InvestigationRole: Writing – review & editing
Louise C. Kenny: Role: InvestigationRole: Writing – review & editing
Iain Buchan: Role: InvestigationRole: Writing – review & editing
Jonathan Wolf: Role: ResourcesRole: Software
Janice Rymer: Role: InvestigationRole: Writing – review & editing
Sebastien Ourselin: Role: InvestigationRole: Writing – review & editing
Claire J. Steves: Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – review
& editing
Timothy D. Spector: Role: ConceptualizationRole: InvestigationRole: Writing – review & editing
Louise R. Newson:
ORCID: https://orcid.org/0000-0002-6756-3823
Role: ConceptualizationRole: InvestigationRole: MethodologyRole: Writing – original
draftRole: Writing – review & editing
Jordana T. Bell: Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole:
SupervisionRole: Writing – original draftRole: Writing – review & editing
Edward Mullins: Role: Editor
Journal
Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
10
September
2021
Publication date Collection: 2021
Publication date PMC-release: 10
September
2021
Volume: 16
Issue: 9
Electronic Location Identifier: e0257051
Affiliations
[1
]
Department of Twin Research and Genetic Epidemiology, King’s College London, London,
United Kingdom
[2
]
School of Biomedical Engineering & Imaging Sciences, King’s College London, London,
United Kingdom
[3
]
Zoe Global Limited, London, United Kingdom
[4
]
National Health Service, London, United Kingdom
[5
]
Department of Women’s and Children’s Health, University of Liverpool, Liverpool, United
Kingdom
[6
]
Department of Public Health, Policy and Systems, University of Liverpool, Liverpool,
United Kingdom
[7
]
Department of Women’s Health, King’s College London, London, United Kingdom
[8
]
Newson Health Menopause & Wellbeing Centre, Stratford-Upon-Avon, United Kingdom
Imperial College London, UNITED KINGDOM
Author notes
Competing Interests: Zoe Global Limited co-developed the app pro bono for non-commercial purposes. JCP
and JW work for Zoe Global, and TDS is a consultant to Zoe Global. IB is Chief Data
Scientist Advisor for AstraZeneca. These do not alter our adherence to PLoS ONE policies
on sharing data and materials.
Author information
Article
Publisher ID:
PONE-D-21-02705
DOI: 10.1371/journal.pone.0257051
PMC ID: 8432854
PubMed ID: 34506535
SO-VID: 64cea5b7-3d6c-4401-9168-af92d0d1d14b
Copyright © © 2021 Costeira et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
History
Date
received
: 4
February
2021
Date
accepted
: 22
August
2021
Page count
Figures: 0,
Tables: 2,
Pages: 14
Funding
Funded by:
zoe global
Funded by:
funder-id http://dx.doi.org/10.13039/100004440, wellcome trust;
Funded by:
medical research council/british heart foundation
Funded by:
Alzheimer’s Society Chronic Disease Research Foundation
Funded by:
Economic and Social Research Council
Award ID: ES/N000404/1
Award Recipient
:
Jordana T. Bell
Funded by:
European Community’s Seventh Framework Programme
Award ID: FP7/2007–2013
Funded by:
National Institute for Health Research
Award ID: BioResource
Funded by:
funder-id http://dx.doi.org/10.13039/501100000272, national institute for health research;
Award ID: NIHR300159
Award Recipient
:
Mary Ni Lochlainn
Zoe Global provided in kind support for all aspects of building, running, and supporting
the app and service to all users worldwide. Investigators received support from the
Wellcome Trust, the MRC/BHF, Alzheimer’s Society, EU, NIHR, CDRF, ESRC. The TwinsUK
study was funded by the Wellcome Trust; European Community’s Seventh Framework Programme
(FP7/2007–2013); National Institute for Health Research (NIHR)- funded BioResource,
Clinical Research Facility and Biomedical Research Centre based at Guy’s and St Thomas’
NHS Foundation Trust in partnership with King’s College London. Epigenetic ageing
estimates were generated from the UK Economic and Social Research Council (ES/N000404/1
to JTB). MNL is supported by an NIHR Doctoral Fellowship (grant code NIHR300159).
Zoe Global provided support in the form of salaries for authors JCP and JW and contributed
to data collection which was carried via the Zoe app. The roles of these authors are
articulated in the ‘Author Contributions’ section. The funders did not have any additional
role in the study design, data analysis, decision to publish, or preparation of the
manuscript.
Categories
Subject:
Research Article
Subject:
Medicine and Health Sciences
Subject:
Medical Conditions
Subject:
Infectious Diseases
Subject:
Viral Diseases
Subject:
Covid 19
Subject:
Biology and Life Sciences
Subject:
Biochemistry
Subject:
Hormones
Subject:
Estrogens
Subject:
Medicine and Health Sciences
Subject:
Pharmaceutics
Subject:
Drug Therapy
Subject:
Hormonal Therapy
Subject:
Biology and Life Sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Virus Testing
Subject:
Biology and Life Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Medicine and Health Sciences
Subject:
Immunology
Subject:
Immune Response
Subject:
Biology and life sciences
Subject:
Cell biology
Subject:
Chromosome biology
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
Chromatin
Subject:
Chromatin modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Biochemistry
Subject:
Nucleic acids
Subject:
DNA
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Epigenetics
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Biology and life sciences
Subject:
Genetics
Subject:
Gene expression
Subject:
DNA modification
Subject:
DNA methylation
Subject:
Medicine and Health Sciences
Subject:
Epidemiology
Subject:
Medical Risk Factors
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