Handedness and speech: A critical reappraisal of the role of genetic and environmental factors in the cerebral lateralization of function.

Abstract

Functional predominance of the left cerebral hemisphere with regard to both handedness and speech has usually been assumed to be due to some underlying neural specialization that is predetermined and inborn. However, data from left-handed individuals and animal experiments, together with a consideration of the effects of natural selection on brain and behaviour during hominid evolution, are incompatible with such an explanation. A critical reexamination of the relevant nonhuman and human evidence suggests that although the development of a cerebral lateralization for speech and handedness is dependent on both genetic and environmental factors, the specific role of inborn and postnatal influences is very different. This has significant implications for a fundamental revision of current theory and research orientation.