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      Phakic intraocular lenses: An overview

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          Abstract

          Phakic intraocular lenses (pIOLs) are a common solution for the surgical correction of high myopia and myopia in thin corneas. Global trends result in increasing rates of patients with high myopia which will result in increased rates of pIOL implantation. Three types of lenses can be distinguished: anterior chamber angle-supported, anterior chamber iris-fixated, and posterior chamber phakic IOLs. The efficacy of phakic intraocular lenses is generally very good, but pIOLs have undergone many changes over the years to improve the safety profile and decrease pIOL-related complications such as endothelial cell loss, corneal decompensation and cataract formation. This article describes the efficacy and safety profiles of the most recent pIOLs, as well as suggests gaps of knowledge that are deserve additional research to optimize the results of pIOLs.

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          Most cited references145

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          Global Prevalence of Myopia and High Myopia and Temporal Trends from 2000 through 2050.

          Myopia is a common cause of vision loss, with uncorrected myopia the leading cause of distance vision impairment globally. Individual studies show variations in the prevalence of myopia and high myopia between regions and ethnic groups, and there continues to be uncertainty regarding increasing prevalence of myopia.
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            The Lens Opacities Classification System III. The Longitudinal Study of Cataract Study Group.

            To develop the Lens Opacities Classification System III (LOCS III) to overcome the limitations inherent in lens classification using LOCS II. These limitations include unequal intervals between standards, only one standard for color grading, use of integer grading, and wide 95% tolerance limits. The LOCS III contains an expanded set of standards that were selected from the Longitudinal Study of Cataract slide library at the Center for Clinical Cataract Research, Boston, Mass. It consists of six slit-lamp images for grading nuclear color (NC) and nuclear opalescence (NO), five retroillumination images for grading cortical cataract (C), and five retroillumination images for grading posterior subcapsular (P) cataract. Cataract severity is graded on a decimal scale, and the standards have regularly spaced intervals on a decimal scale. The 95% tolerance limits are reduced from 2.0 for each class with LOCS II to 0.7 for nuclear opalescence, 0.7 for nuclear color, 0.5 for cortical cataract, and 1.0 for posterior subcapsular cataract with the LOCS III, with excellent interobserver agreement. The LOCS III is an improved LOCS system for grading slit-lamp and retroillumination images of age-related cataract.
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              Is Open Access

              Efficacy Comparison of 16 Interventions for Myopia Control in Children: A Network Meta-analysis.

              To determine the effectiveness of different interventions to slow down the progression of myopia in children.
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                Author and article information

                Journal
                Indian J Ophthalmol
                Indian J Ophthalmol
                IJO
                Indian Journal of Ophthalmology
                Wolters Kluwer - Medknow (India )
                0301-4738
                1998-3689
                December 2020
                23 November 2020
                : 68
                : 12
                : 2779-2796
                Affiliations
                [1 ]University Eye Clinic Maastricht, Maastricht University Medical Center, Maastricht, The Netherlands
                [2 ]Department of Ophthalmology, University Hospitals KU Leuven, Leuven, Belgium
                [3 ]Department of Ophthalmology, Zuyderland Medical Center, Heerlen, The Netherlands
                Author notes
                Correspondence to: Dr. Soraya M R Jonker, University Eye Clinic Maastricht, Maastricht University Medical Center, PO Box 5800, 6202 AZ, Maastricht, The Netherlands. E-mail: soraya.jonker@ 123456mumc.nl
                Article
                IJO-68-2779
                10.4103/ijo.IJO_2995_20
                7856940
                33229653
                65e0bf9a-d286-4eeb-bf67-13c336cbb123
                Copyright: © 2020 Indian Journal of Ophthalmology

                This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.

                History
                : 15 September 2020
                : 16 October 2020
                : 03 November 2020
                Categories
                Review Article

                Ophthalmology & Optometry
                phakic intraocular lens,high myopia,refractive surgery
                Ophthalmology & Optometry
                phakic intraocular lens, high myopia, refractive surgery

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