Circulating miR-181a-5p as a new biomarker for acute cellular rejection in heart transplantation.

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Abstract

Acute cellular rejection (ACR) is a major complication in heart transplantation (HTx). Endomyocardial biopsy is the reference method for early detection of ACR, but a new non-invasive approach is needed. Tentative candidates could be circulating microRNAs. This study aimed to discover and validate microRNAs in serum for ACR detection after HTx.

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Journal

Journal ID (iso-abbrev): J Heart Lung Transplant

Title: The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation

Publisher: Elsevier BV

ISSN (Electronic): 1557-3117

ISSN (Print): 1053-2498

Publication date (Electronic): October 2020

Volume: 39

Issue: 10

Affiliations

[1 ] Grupo de investigación en Cardiología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade da Coruña (UDC), Spain.

[2 ] Servicio de Cardiología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), CIBERCV, SERGAS, Universidade da Coruña (UDC), Spain.

[3 ] Grupo de investigación en Cardiología, Instituto de Investigación Biomédica de A Coruña (INIBIC), Complexo Hospitalario Universitario de A Coruña (CHUAC), SERGAS, Universidade da Coruña (UDC), Spain.. Electronic address: lucia.nunez@udc.es.

[4 ] Servicio de Anatomía Patológica, Complexo Hospitalario Universitario de A Coruña (CHUAC) SERGAS, A Coruña, Spain.

Article

Publisher Item ID: S1053-2498(20)31581-3

DOI: 10.1016/j.healun.2020.05.018

PubMed ID: 32654912

SO-VID: 68848dc7-59b2-402b-b6e9-40653dffcf2d

History

Keywords: acute rejection,biomarker,heart transplantation,miR-181a-5p,microRNA

Data availability:

Keywords: acute rejection, biomarker, heart transplantation, miR-181a-5p, microRNA

Circulating miR-181a-5p as a new biomarker for acute cellular rejection in heart transplantation.

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Abstract

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Journal of Circulating Biomarkers

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