For Publishers
DiscoveryMetadataPeer reviewHostingPublishing
For Researchers
JoinPublishReviewCollect
Register
Blog
About
Search
Advanced search
My ScienceOpen
Search
For Publishers
For Researchers
Blog
About
7
views
34
references
 Top references
cited by
74
    
0 reviews
 Review
0
comments
 Comment
0
recommends
+1 Recommend
0 collections
    0
    shares
      3,249
      similar
       All similar
      • Record: found
      • Abstract: not found
      • Article: not found

      Persistent Physical Symptoms as Perceptual Dysregulation : A Neuropsychobehavioral Model and Its Clinical Implications

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The mechanisms underlying the perception and experience of persistent physical symptoms are not well understood, and in the models, the specific relevance of peripheral input versus central processing, or of neurobiological versus psychosocial factors in general, is not clear. In this article, we proposed a model for this clinical phenomenon that is designed to be coherent with an underlying, relatively new model of the normal brain functions involved in the experience of bodily signals.

          Related collections

          Most cited references34

          • Record: found
          • Abstract: found
          • Article: not found
          Is Open Access

          Interoceptive inference, emotion, and the embodied self.

          Anil K. Seth (2013)
          The concept of the brain as a prediction machine has enjoyed a resurgence in the context of the Bayesian brain and predictive coding approaches within cognitive science. To date, this perspective has been applied primarily to exteroceptive perception (e.g., vision, audition), and action. Here, I describe a predictive, inferential perspective on interoception: 'interoceptive inference' conceives of subjective feeling states (emotions) as arising from actively-inferred generative (predictive) models of the causes of interoceptive afferents. The model generalizes 'appraisal' theories that view emotions as emerging from cognitive evaluations of physiological changes, and it sheds new light on the neurocognitive mechanisms that underlie the experience of body ownership and conscious selfhood in health and in neuropsychiatric illness. Copyright © 2013 Elsevier Ltd. All rights reserved.
          Article 0 comments Cited 497 times – based on 0 reviews     Review now
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Interoceptive predictions in the brain.

            Lisa Feldman Barrett, W Simmons (2015)
            Intuition suggests that perception follows sensation and therefore bodily feelings originate in the body. However, recent evidence goes against this logic: interoceptive experience may largely reflect limbic predictions about the expected state of the body that are constrained by ascending visceral sensations. In this Opinion article, we introduce the Embodied Predictive Interoception Coding model, which integrates an anatomical model of corticocortical connections with Bayesian active inference principles, to propose that agranular visceromotor cortices contribute to interoception by issuing interoceptive predictions. We then discuss how disruptions in interoceptive predictions could function as a common vulnerability for mental and physical illness.
            Article 0 comments Cited 465 times – based on 0 reviews     Review now
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              An active inference theory of allostasis and interoception in depression.

              Lisa Feldman Barrett, Karen Quigley, Paul Hamilton (2016)
              In this paper, we integrate recent theoretical and empirical developments in predictive coding and active inference accounts of interoception (including the Embodied Predictive Interoception Coding model) with working hypotheses from the theory of constructed emotion to propose a biologically plausible unified theory of the mind that places metabolism and energy regulation (i.e. allostasis), as well as the sensory consequences of that regulation (i.e. interoception), at its core. We then consider the implications of this approach for understanding depression. We speculate that depression is a disorder of allostasis, whose myriad symptoms result from a 'locked in' brain that is relatively insensitive to its sensory context. We conclude with a brief discussion of the ways our approach might reveal new insights for the treatment of depression.This article is part of the themed issue 'Interoception beyond homeostasis: affect, cognition and mental health'.
              Article 0 comments Cited 158 times – based on 0 reviews     Review now
                Bookmark
                All references

                Author and article information

                Journal
                Title: Psychosomatic Medicine
                Abbreviated Title: Psychosomatic Medicine
                Publisher: Ovid Technologies (Wolters Kluwer Health)
                ISSN (Print): 0033-3174
                Publication date Created: 2018
                Publication date (Print): June 2018
                Volume: 80
                Issue: 5
                Pages: 422-431
                Article
                DOI: 10.1097/PSY.0000000000000588
                PubMed ID: 29621046
                SO-VID: 68c10e06-599e-4be5-970d-a8a163332f6c
                Copyright © © 2018
                History

                Data availability:

                Comments

                Comment on this article

                scite_

                Similar content3,249

                See all similar

                Cited by70

                See all cited by

                Most referenced authors394

                See all reference authors