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      Fluorescent Nanobiosensors for Sensing Glucose

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          Abstract

          Glucose sensing in diabetes diagnosis and therapy is of great importance due to the prevalence of diabetes in the world. Furthermore, glucose sensing is also critical in the food and drug industries. Sensing glucose has been accomplished through various strategies, such as electrochemical or optical methods. Novel transducers made with nanomaterials that integrate fluorescent techniques have allowed for the development of advanced glucose sensors with superior sensitivity and convenience. In this review, glucose sensing by fluorescent nanobiosensor systems is discussed. Firstly, typical fluorescence emitting/interacting nanomaterials utilized in various glucose assays are discussed. Secondly, strategies for integrating fluorescent nanomaterials and biological sensing elements are reviewed and discussed. In summary, this review highlights the applicability of fluorescent nanomaterials, which makes them ideal for glucose sensing. Insight on the future direction of fluorescent nanobiosensor systems is also provided.

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                Author and article information

                Journal
                Sensors (Basel)
                Sensors (Basel)
                sensors
                Sensors (Basel, Switzerland)
                MDPI
                1424-8220
                05 May 2018
                May 2018
                : 18
                : 5
                : 1440
                Affiliations
                [1 ]Department of Chemical and Biochemical Engineering, University of Western Ontario, 1151 Richmond St., London, ON N6A 5B9, Canada; lchen449@ 123456uwo.ca
                [2 ]Biomedical Engineering Graduate Program, University of Western Ontario, 1151 Richmond St., London, ON N6A 5B9, Canada; ehwang8@ 123456uwo.ca
                Author notes
                [* ]Correspondence: jzhang@ 123456eng.uwo.ca ; Tel.: +1 519-661-2111 (ext. 88322)
                Author information
                https://orcid.org/0000-0002-6875-8008
                Article
                sensors-18-01440
                10.3390/s18051440
                5982147
                29734744
                6cbded07-ef3e-4ea6-8aa5-6e93b4594825
                © 2018 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 28 March 2018
                : 02 May 2018
                Categories
                Review

                Biomedical engineering
                glucose sensing,fluorescent nanomaterials,fluorescent nanobiosensors,sensitivity and selectivity

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