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      Benign gastro-colic fistula in a woman presenting with weight loss and intermittent vomiting: a case report

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      1 , , 1 , 1
      Journal of Medical Case Reports
      BioMed Central

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          Abstract

          Introduction

          Benign gastro-colic fistula is a rare occurrence in modern surgery due to the progress in medical management of gastric ulcer disease. Here we report the first case of benign gastro-colic fistula occurring whilst on proton-pump inhibitor therapy. This is a case study of benign gastro-colic fistula and review of the available literature in regards to etiology, diagnosis, management and prognosis.

          Case presentation

          An 84-year-old woman of Caucasian background presented with 12 months of worsening abdominal pain, nausea, vomiting, diarrhea and weight loss on a background of known gastric ulcer disease.

          Conclusion

          The leading cause of gastro-colic fistulae has changed from benign to malignant due to improved medical management of gastric ulcer disease. The rarity and non-specific symptoms of gastro-colic fistula make the diagnosis difficult and it is best made by barium enema; however, computed tomography has not been formally evaluated. Surgical management with en bloc resection of the fistula tract is the preferred treatment. Benign gastro-colic fistulae are becoming exceedingly rare in the context of modern medical management of gastric ulcer disease. Surgical management is the gold standard for both benign and malignant disease.

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          Most cited references7

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          Long-term survival from gastrocolic fistula secondary to adenocarcinoma of the transverse colon

          Background Gastrocolic fistula is a rare presentation of both benign and malignant diseases of the gastrointestinal tract. Malignant gastrocolic fistula is most commonly associated with adenocarcinoma of the transverse colon in the Western World. Despite radical approaches to treatment, long-term survival is rarely documented. Case presentation We report a case of a 24-year-old woman who presented with the classic triad of symptoms associated with gastrocolic fistula. Radical en-bloc surgery and adjuvant chemotherapy were performed. She is still alive ten years after treatment. Conclusions Gastrocolic fistula is an uncommon presentation of adenocarcinoma of the transverse colon. Radical en-bloc surgery with adjuvant chemotherapy may occasionally produce long-term survival.
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            Outcomes in the management of gastrocolic fistulas: a single surgical unit's experience.

            Gastrocolic fistula has been associated with a variety of diseases. Causative factors are most commonly gastric/colonic cancers and benign gastric ulcers. Treatment modalities may change according to etiology. In this study, we present our cases with gastrocolic fistula and the treatment modalities utilized for this uncommon complication. The records of the patients with gastrocolic fistula between November 1996 and June 2006 were retrospectively analyzed. Six patients with a mean age of 57.5 were determined. Of these, four had malignancy and two had gastric ulcer. The predominant symptoms were diarrhea and vomiting, weight loss, and abdominal pain. Diagnostic studies included barium enema, endoscopy, barium meal, colonoscopy, and computed tomography. After preoperative nutritional support, en-bloc resection of the involved gastrocolic region (4), simple excision (1), and wedge resection of the gastric part and closure of the colonic wall (1) were performed. One patient died of respiratory disorders and there was only one recurrence. In our series, therapeutic management for this unusual disorder included various resection procedures such as simple excision, which may result in recurrence, and wedge resection or en-bloc resection for benign cases, whereas en-bloc resection and reconstruction procedures remained the most applied management for malignant cases. En-bloc resection followed by combination of adjuvant chemotherapy results in long disease-free survival. Gastrocolic fistula should be suspected in patients with chronic diarrhea and vomiting of unknown cause with a high suspicion of gastrointestinal malignancy.
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              Nonsteroidal anti-inflammatory drugs and gastrocolic fistula.

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                Author and article information

                Journal
                J Med Case Reports
                Journal of Medical Case Reports
                BioMed Central
                1752-1947
                2011
                14 July 2011
                : 5
                : 313
                Affiliations
                [1 ]St Vincent's Hospital Melbourne, PO Box 2900 Fitzroy, Victoria 3065, Australia
                Article
                1752-1947-5-313
                10.1186/1752-1947-5-313
                3155123
                21756322
                751208b6-4f2c-43c4-a0d8-8eb26119036c
                Copyright ©2011 Barrett et al; licensee BioMed Central Ltd.

                This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 5 January 2011
                : 14 July 2011
                Categories
                Case Report

                Medicine
                Medicine

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