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      Sperm guidance in mammals - an unpaved road to the egg.

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          Abstract

          Contrary to the prevalent view, there seems to be no competition in the mammalian female genital tract among large numbers of sperm cells that are racing towards the egg. Instead, small numbers of the ejaculated sperm cells enter the Fallopian tube, and these few must be guided to make the remaining long, obstructed way to the egg. Here, we review the mechanisms by which mammalian sperm cells are guided to the egg.

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          Author and article information

          Journal
          Nat Rev Mol Cell Biol
          Nature reviews. Molecular cell biology
          Springer Science and Business Media LLC
          1471-0072
          1471-0072
          Apr 2006
          : 7
          : 4
          Affiliations
          [1 ] Department of Biological Chemistry, the Weizmann Institute of Science, 76100 Rehovot, Israel. m.eisenbach@weizmann.ac.il
          Article
          nrm1893
          10.1038/nrm1893
          16607290
          78498dd7-705b-4e54-8115-a69828954014
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