19
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Suicidal Ingestion of Potassium Permanganate Crystals: A Rare Encounter

      case-report

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Potassium permanganate poisoning is not common. Although Symptoms of potassium permanganate ingestion are gastrointestinal and Complications due to ingestion of potassium permanganate include cardiovascular depression, hepatic and renal damage, upper airway obstruction, bleeding tendency and methemoglobinemia. Gastric damage due to potassium permanganate has rarely been reported previously. We are reporting a 34-year old female patient who presented to our Emergency Department after suicidal ingestion of potassium permanganate crystals. After treatment, the patient was discharged home on the 8 th day after admission. So we conclude that Emergency endoscopy has a significant role in diagnosis and management of potassium permanganate ingestion.

          Related collections

          Most cited references19

          • Record: found
          • Abstract: found
          • Article: not found

          Unintentional ingestion of potassium permanganate.

          This case of an unintentional ingestion of an unknown amount of potassium permanganate by a 5-year-old boy, and its sequelae, exemplifies the potential danger of this poison. Due to the wide availability of this agent in over-the-counter preparations and the high potential for serious sequelae, clinicians should be aware of the actions of this agent, as well as the diagnostic and management features associated with it.
            Bookmark
            • Record: found
            • Abstract: found
            • Article: not found

            Potassium permanganate poisoning--a rare cause of fatal self poisoning.

            Attempted suicide by self poisoning is common because of the ready availability of drugs, whether prescribed or bought over the counter. In some cases, the ingestion of seemingly innocuous household products or chemicals can result in death. Potassium permanganate is an example. Poisoning with potassium permanganate can be fatal when a significant amount is ingested, as shown by a patient who suffered both the corrosive and systemic toxic effects of this chemical.
              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Fatal acute hepatorenal failure following potassium permanganate ingestion.

              Potassium permanganate (KMnO4), a powerful oxidizing agent, is readily available without prescription. Tissue contact produces coagulation necrosis and the lethal consequences of oral ingestion are well described, with most deaths because of airway oedema and obstruction or circulatory collapse. Whilst systemic toxicity is reported, its mechanism is unclear. We describe a case of suicidal ingestion of KMnO4 followed by acute hepatorenal toxicity resulting in the death of the patient. The clinical course bore close resemblance to that of severe paracetamol overdose. We discuss the pathogenesis of the systemic toxicity of KMnO4 and postulate that it is due to oxidative injury from free radicals generated by the absorbed permanganate ion. We recommend that N-acetyl cysteine be given within the first few hours to all patients with potassium permanganate poisoning.
                Bookmark

                Author and article information

                Journal
                Toxicol Int
                Toxicol Int
                TI
                Toxicology International
                Medknow Publications & Media Pvt Ltd (India )
                0971-6580
                0976-5131
                Sep-Dec 2014
                : 21
                : 3
                : 331-334
                Affiliations
                [1]Department of Emergency Medicine, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India
                [1 ]Department of Medical Gastroenterology, Vydehi Institute of Medical Sciences and Research Centre, Bangalore, Karnataka, India
                Author notes
                Address for correspondence: Dr. Ravikanti Karthik, 3 rd Year Pg in Department of Emergency Medicine, Vydehi Institute of Medical Sciences and Research Centre, #82, Epip Area, Whitefield, Bangalore - 560 066, Karnataka, India. E-mail: karthik.ravikanti@ 123456yahoo.in
                Article
                TI-21-331
                10.4103/0971-6580.155392
                4413422
                7c54b87f-6c15-4ddd-9cb7-ea289d58f17c
                Copyright: © Toxicology International

                This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                Categories
                Case Report

                Toxicology
                emergency department,emergency endoscopy,gastric damage,potassium permanganate crystals

                Comments

                Comment on this article