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      Clinical efficacy of Vyaghriharitaki Avaleha in the management of chronic bronchitis

      research-article
      Author(s): , 1
      Publication date (Print):
      Journal: Ayu
      Publisher: Medknow Publications & Media Pvt Ltd
      Keywords: Chronic bronchitis, Kasa, Vyaghriharitaki Avaleha

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          Abstract

          Introduction:

          Vyaghriharitaki Avaleha (VHA), a polyherbal classical Ayurvedic formulation has been used in Kasa (cough), Swasa (asthma), Rajayakshma (tuberculosis) etc., conditions.

          Aim:

          To evaluate the clinical efficacy of VHA in the management of chronic bronchitis.

          Materials and Methods:

          Patients of chronic bronchitis were given 10 g of VHA twice a day with lukewarm water before meals for 12 weeks. Improvement in clinical symptoms of chronic bronchitis as the primary outcome measures and St. George's Respiratory Questionnaire scores as secondary outcome measure was studied.

          Results:

          Out of 66 enrolled patients, 61 completed the treatment schedule. The results show that VHA provides statistically significant improvement with P < 0.001 in both primary and secondary outcome measures.

          Conclusion:

          VHA can be considered as a safe and effective formulation in the management of chronic bronchitis.

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          Most cited references9

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          Further studies on the clinical efficacy of Solanum xanthocarpum and Solanum trilobatum in bronchial asthma.

          R Alagappan, V Vijayasekaran, S Govindan … (2004)
          The clinical efficacy of two herbs S. xanthocarpum and S. trilobatum in a dose of 300 mg tds for 3 days was investigated in mild to moderate bronchial asthma. Their effect was compared with standard bronchodilator drugs, salbutamol (4 mg) and deriphylline (200 mg). The respiratory function was assessed by measuring the peak expiratory flow rate (PEFR) using a mini peak flow meter. In addition, improvement in lung function was assessed by physical examination (rhonchi and crepitation) and other symptoms such as cough, breathlessness and sputum. S. xanthocarpum and S. trilobatum produced a progressive improvement in the ventilatory function of asthmatic individuals over 3 days. The scores for rhonchi, cough, breathlessness and sputum were decreased by these drug treatments. The improvement in PEFR and the reduction in other symptom scores clearly indicate a bronchodilator effect, a decrease of oedema and secretions in the airway lumen. The response to these herbs can be considered to be equivalent to that of deriphylline but less than salbutamol. No untoward effects were reported during the study. The present study further confirms the traditional use of these herbs in bronchial asthma.
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            Harrisons's Principles of Internal Medicine

            LW Powell, DL Kasper, A. Fauci … (2005)
            Article 0 comments Cited 2 times – based on 0 reviews     Review now
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              Immunomodulatory activity of alcohol extract of Terminalia chebula Retz. combretaceae

              Aher V., V Aher, AK Wahi (2011)
              Article 0 comments Cited 2 times – based on 0 reviews     Review now
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                Author and article information

                Journal
                Journal ID (nlm-ta): Ayu
                Journal ID (iso-abbrev): Ayu
                Journal ID (publisher-id): AYU
                Title: Ayu
                Publisher: Medknow Publications & Media Pvt Ltd (India )
                ISSN (Print): 0974-8520
                ISSN (Electronic): 0976-9382
                Publication date (Print): Jan-Mar 2015
                Volume: 36
                Issue: 1
                Pages: 50-55
                Affiliations
                [1]Department of Kaumarbhritya, Shri Shirdi Saibaba Ayurved College, Renwal, Jaipur, Rajasthan, India
                [1 ]Ayurveda Chair, Department of Pharmacology and Phytotherapy, Medical School, University of Debrecen, Debrecen, Hungary
                Author notes
                Address for correspondence: Dr. Jaiprakash Ram, C/O. Dr. Ranjita Vaghamshi, 2. Amarnath Plot, Behind Mahila College, Rajkot - 360 007, Gujarat, India. E-mail: jpram236@ 123456gmail.com
                Article
                Publisher ID: AYU-36-50
                DOI: 10.4103/0974-8520.169009
                PMC ID: 4687240
                SO-VID: 7d971828-afad-47ef-b096-b013fb26bf73
                Copyright © Copyright: © AYU (An International Quarterly Journal of Research in Ayurveda)
                License:

                This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

                History
                Categories
                Subject: Clinical Research

                ScienceOpen disciplines: Complementary & Alternative medicine
                Keywords: chronic bronchitis,kasa,vyaghriharitaki avaleha
                Data availability:
                ScienceOpen disciplines: Complementary & Alternative medicine
                Keywords: chronic bronchitis, kasa, vyaghriharitaki avaleha

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