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      A History of Eclampsia, Toxemia and the Kidney in Pregnancy


      American Journal of Nephrology

      S. Karger AG

      Pregnancy, Eclampsia, Toxemia, Proteinuria

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          Eclampsia, accompanied by convulsions, is one of the most dangerous complications of pregnant women. This condition was known to the ancient Greeks, who named it eclampsia. Prior to the 18th century, the term eclampsia was used only to refer to the visual phenomena which accompanied the neurologic aspects of the malady. Rayer’s landmark contribution (1839–1841) provided evidence for renal involvement with the observation of protein in the urine of pregnant, edematous women. Lever (1843) reported finding proteinuria in eclampsia and concluded that disappearance of proteinuria after delivery of the child was evidence that eclampsia was different from Bright’s disease.

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          Author and article information

          Am J Nephrol
          American Journal of Nephrology
          S. Karger AG
          April 1999
          23 April 1999
          : 19
          : 2
          : 313-319
          Renal Division, Department of Medicine, and The Bernard Becker Medical Library, Washington University School of Medicine, St. Louis, Mo., USA
          13467 Am J Nephrol 1999;19:313–319
          © 1999 S. Karger AG, Basel

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          Page count
          Figures: 7, References: 33, Pages: 7
          Self URI (application/pdf): https://www.karger.com/Article/Pdf/13467
          Origins of Nephrology – The Modern Era

          Cardiovascular Medicine, Nephrology

          Toxemia, Eclampsia, Pregnancy, Proteinuria


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