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      Horizontal GBR with anorganic equine bone combined with a customized titanium mesh

      case-report

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          Key Clinical Message

          This case report describes the fixed rehabilitation of the lower left arch in a patient following an horizontal GBR procedure by means of a customized titanium mesh and a new slow resorption bone substitute of equine origin.

          Abstract

          Titanium Mesh application and tissue adaptation.

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          Most cited references35

          • Record: found
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          Guided bone regeneration: materials and biological mechanisms revisited

          Guided bone regeneration (GBR) is commonly used in combination with the installment of titanium implants. The application of a membrane to exclude non‐osteogenic tissues from interfering with bone regeneration is a key principle of GBR. Membrane materials possess a number of properties which are amenable to modification. A large number of membranes have been introduced for experimental and clinical verification. This prompts the need for an update on membrane properties and the biological outcomes, as well as a critical assessment of the biological mechanisms governing bone regeneration in defects covered by membranes. The relevant literature for this narrative review was assessed after a MEDLINE/PubMed database search. Experimental data suggest that different modifications of the physicochemical and mechanical properties of membranes may promote bone regeneration. Nevertheless, the precise role of membrane porosities for the barrier function of GBR membranes still awaits elucidation. Novel experimental findings also suggest an active role of the membrane compartment per se in promoting the regenerative processes in the underlying defect during GBR, instead of being purely a passive barrier. The optimization of membrane materials by systematically addressing both the barrier and the bioactive properties is an important strategy in this field of research.
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            The long-term efficacy of currently used dental implants: a review and proposed criteria of success.

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              "PASS" principles for predictable bone regeneration.

              Guided bone regeneration is a well-established technique used for augmentation of deficient alveolar ridges. Predictable regeneration requires both a high level of technical skill and a thorough understanding of underlying principles of wound healing. This article describes the 4 major biologic principles (i.e., PASS) necessary for predictable bone regeneration: primary wound closure to ensure undisturbed and uninterrupted wound healing, angiogenesis to provide necessary blood supply and undifferentiated mesenchymal cells, space maintenance/creation to facilitate adequate space for bone ingrowth, and stability of wound and implant to induce blood clot formation and uneventful healing events. In addition, a novel flap design and clinical cases using this principle are presented.
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                Author and article information

                Contributors
                francescoorlando93@yahoo.com
                Journal
                Clin Case Rep
                Clin Case Rep
                10.1002/(ISSN)2050-0904
                CCR3
                Clinical Case Reports
                John Wiley and Sons Inc. (Hoboken )
                2050-0904
                23 April 2024
                April 2024
                : 12
                : 4 ( doiID: 10.1002/ccr3.v12.4 )
                : e8780
                Affiliations
                [ 1 ] Private Practice, Centro Odontoiatrico e Protesico Civitali S.R.L. Milan Italy
                [ 2 ] Dental School Vita‐Salute University IRCCS San Raffaele Milan Italy
                [ 3 ] Department of Biomedical Surgical and Dental Sciences Università Degli Studi di Milano Milan Italy
                [ 4 ] Department of Dentistry Vita‐Salute San Raffaele University Milan Milan Italy
                Author notes
                [*] [* ] Correspondence

                Francesco Orlando, Centro Odontoiatrico e Protesico Civitali S.R.L., Milan, Italy.

                Email: francescoorlando93@ 123456yahoo.com

                Author information
                https://orcid.org/0009-0004-1108-2184
                Article
                CCR38780 CCR3-2023-12-2852
                10.1002/ccr3.8780
                11039487
                38659499
                81881ee9-0669-478f-a36a-be03f907b8d9
                © 2024 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 13 February 2024
                : 27 March 2024
                Page count
                Figures: 9, Tables: 0, Pages: 7, Words: 3900
                Funding
                Funded by: Bioteck Spa
                Categories
                Dentistry
                Surgery
                Case Report
                Case Report
                Custom metadata
                2.0
                April 2024
                Converter:WILEY_ML3GV2_TO_JATSPMC version:6.4.0 mode:remove_FC converted:23.04.2024

                anorganic bone,equine bone graft,guided bone regeneration,xenograft

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