Application of platelet/lymphocyte and neutrophil/lymphocyte ratios in early diagnosis and prognostic prediction in patients with resectable gastric cancer.

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Abstract

Gastric cancer is the fourth most frequent cancer and the second cause of cancer-related deaths worldwide. China has a high incidence of gastric cancer. Inflammation is a critical component of tumor progression. It has been widely accepted that gastric cancer is an inflammation-driven cancer. In this study, we investigated the application value of systemic inflammatory response (SIR) markers, platelet to lymphocyte ratio (PLR) and neutrophil to lymphocyte ratio (NLR), in early diagnosis and prognostic prediction in patients with resectable gastric cancer.

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Journal

Journal ID (iso-abbrev): Cancer Biomark

Title: Cancer biomarkers : section A of Disease markers

Publisher: IOS Press

ISSN (Electronic): 1875-8592

ISSN (Print): 1574-0153

Publication date (Electronic): 2015

Volume: 15

Issue: 6

Affiliations

[1 ] Department of Oncology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

[2 ] Department of Oncology, Suzhou Xiangcheng People's Hospital, Suzhou, Jiangsu, China.

[3 ] Department of Radiation Oncology, Lianyungang First People's Hospital, Lianyungang, Jiangsu, China.

[4 ] The Fourth Clinical Medical College, Nanjing Medical University, Nanjing, Jiangsu, China.

[5 ] Department of Radiation Oncology, Xuzhou Central Hospital, Xuzhou, Jiangsu, China.

[6 ] Department of General Surgery, Suzhou Xiangcheng People's Hospital, Suzhou, Jiangsu, China.

[7 ] Department of Minimally Invasive Surgery, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

[8 ] Department of Hematology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu, China.

[9 ] Jiangsu Institute of Clinical Immunology, Suzhou, Jiangsu, China.

[10 ] Institute of Medical Biotechnology, Soochow University, Suzhou, Jiangsu, China.

[11 ] PREMED Key Laboratory for Precision Medicine, Soochow University, Suzhou, Jiangsu, China.

Article

Publisher Item ID: CBM--1-CBM534

DOI: 10.3233/CBM-150534

PubMed ID: 26444485

SO-VID: 8e8d3413-d701-4100-91e3-fe27ff585024

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Keywords: Gastric cancer,neutrophil to lymphocyte ratio (NLR),platelet to lymphocyte ratio (PLR)

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Keywords: Gastric cancer, neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR)

Application of platelet/lymphocyte and neutrophil/lymphocyte ratios in early diagnosis and prognostic prediction in patients with resectable gastric cancer.

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Karger: Oncology

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