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      Multimodal care for the management of musculoskeletal disorders of the elbow, forearm, wrist and hand: a systematic review by the Ontario Protocol for Traffic Injury Management (OPTIMa) Collaboration

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          Abstract

          Background

          Musculoskeletal disorders of the elbow, forearm, wrist and hand are associated with pain, functional impairment and decreased productivity in the general population. Combining several interventions in a multimodal program of care is reflective of current clinical practice; however there is limited evidence to support its effectiveness. The purpose of our review was to investigate the effectiveness of multimodal care for the management of musculoskeletal disorders of the elbow, forearm, wrist and hand on self-rated recovery, functional recovery, or clinical outcomes in adults or children.

          Methods

          We conducted a systematic review of the literature and best evidence synthesis. We searched MEDLINE, EMBASE, CINAHL, PsycINFO, and the Cochrane Central Register of Controlled Trials from January 1990 to March 2015. Randomized controlled trials, cohort studies, and case–control studies were eligible. Random pairs of independent reviewers screened studies for relevance and critically appraised relevant studies using the Scottish Intercollegiate Guidelines Network criteria. Studies with a low risk of bias were synthesized following best evidence synthesis principles.

          Results

          We screened 5989 articles, and critically appraised eleven articles. Of those, seven had a low risk of bias; one addressed carpal tunnel syndrome and six addressed lateral epicondylitis. Our search did not identify any low risk of bias studies examining the effectiveness of multimodal care for the management of other musculoskeletal disorders of the elbow, forearm, wrist or hand. The evidence suggests that multimodal care for the management of lateral epicondylitis may include education, exercise (strengthening, stretching, occupational exercise), manual therapy (manipulation) and soft tissue therapy (massage). The evidence does not support the use of multimodal care for the management of carpal tunnel syndrome.

          Conclusions

          The current evidence on the effectiveness of multimodal care for musculoskeletal disorders of the elbow, forearm, wrist and hand is limited. The available evidence suggests that there may be a role for multimodal care in the management of patients with persistent lateral epicondylitis. Future research is needed to examine the effectiveness of multimodal care and guide clinical practice.

          Systematic review registration number

          CRD42014009093

          Electronic supplementary material

          The online version of this article (doi:10.1186/s12998-016-0089-8) contains supplementary material, which is available to authorized users.

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          Most cited references56

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          Randomized, Controlled Trials, Observational Studies, and the Hierarchy of Research Designs

          New England Journal of Medicine, 342(25), 1887-1892
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            Prevalence of carpal tunnel syndrome in a general population.

            Carpal tunnel syndrome (CTS) is a cause of pain, numbness, and tingling in the hands and is an important cause of work disability. Although high prevalence rates of CTS in certain occupations have been reported, little is known about its prevalence in the general population. To estimate the prevalence of CTS in a general population. General health mail survey sent in February 1997, inquiring about symptoms of pain, numbness, and tingling in any part of the body, followed 2 months later by clinical examination and nerve conduction testing of responders reporting symptoms in the median nerve distribution in the hands, as well as of a sample of those not reporting these symptoms (controls). A region in southern Sweden with a population of 170000. A sex- and age-stratified sample of 3000 subjects (age range, 25-74 years) was randomly selected from the general population register and sent the survey, with a response rate of 83% (n = 2466; 46% men). Of the symptomatic responders, 81% underwent clinical examination. Population prevalence rates, calculated as the number of symptomatic responders diagnosed on examination as having clinically certain CTS and/or electrophysiological median neuropathy divided by the total number of responders. Of the 2466 responders, 354 reported pain, numbness, and/or tingling in the median nerve distribution in the hands (prevalence, 14.4%; 95% confidence interval [CI], 13.0%-15.8%). On clinical examination, 94 symptomatic subjects were diagnosed as having clinically certain CTS (prevalence, 3.8%; 95% CI, 3.1%-4.6%). Nerve conduction testing showed median neuropathy at the carpal tunnel in 120 symptomatic subjects (prevalence, 4.9%; 95% CI, 4.1%-5.8%). Sixty-six symptomatic subjects had clinically and electrophysiologically confirmed CTS (prevalence, 2.7%; 95% CI, 2.1%-3.4%). Of 125 control subjects clinically examined, electrophysiological median neuropathy was found in 23 (18.4%; 95% CI, 12.0%-26.3%). Symptoms of pain, numbness, and tingling in the hands are common in the general population. Based on our data, 1 in 5 symptomatic subjects would be expected to have CTS based on clinical examination and electrophysiologic testing.
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              An evidence-based practice guideline for the peer review of electronic search strategies.

              Complex and highly sensitive electronic literature search strategies are required for systematic reviews; however, no guidelines exist for their peer review. Poor searches may fail to identify existing evidence because of inadequate recall (sensitivity) or increase the resource requirements of reviews as a result of inadequate precision. Our objective was to create an annotated checklist for electronic search strategy peer review. A systematic review of the library and information retrieval literature for important elements in electronic search strategies was conducted, along with a survey of individuals experienced in systematic review searching. Six elements with a strong consensus as to their importance in peer review were accurate translation of the research question into search concepts, correct choice of Boolean operators and of line numbers, adequate translation of the search strategy for each database, inclusion of relevant subject headings, and absence of spelling errors. Seven additional elements had partial support and are included in this guideline. This evidence-based guideline facilitates the improvement of search quality through peer review, and thus the improvement in quality of systematic reviews. It is relevant for librarians/information specialists, journal editors, developers of knowledge translation tools, research organizations, and funding bodies.
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                Author and article information

                Contributors
                deborah.sutton@uoit.ca
                dgross@ualberta.ca
                pierre.cote@uoit.ca
                kristi.randhawa@uoit.ca
                hainan.yu@uoit.ca
                jessica.wong@uoit.ca
                pstern@cmcc.ca
                s5varatharajan@uwaterloo.ca
                dsoutherst@gmail.com
                heather.shearer@uoit.ca
                maja.stupar@utoronto.ca
                rachel.goldgrub@gmail.com
                gabrielle.vandervelde@theta.utoronto.ca
                dmn2@nyu.edu
                lcarroll@ualberta.ca
                anne.taylorvaisey@uoit.ca
                Journal
                Chiropr Man Therap
                Chiropr Man Therap
                Chiropractic & Manual Therapies
                BioMed Central (London )
                2045-709X
                7 March 2016
                7 March 2016
                2016
                : 24
                : 8
                Affiliations
                [ ]UOIT-CMCC Centre for the Study of Disability Prevention and Rehabilitation, University of Ontario Institute of Technology (UOIT) and Canadian Memorial Chiropractic College (CMCC), 6100 Leslie Street, Toronto, Ontario Canada M2H 3J1
                [ ]Division of Graduate Education and Research, Canadian Memorial Chiropractic College (CMCC), 6100 Leslie Street, Toronto, Ontario Canada M2H 3J1
                [ ]Faculty of Rehabilitation Medicine, Department of Physical Therapy, University of Alberta, 8205 114 St, 3-28 Corbett Hall, Edmonton, AB Canada T6G 2G4
                [ ]Rehabilitation Research Centre, University of Alberta, 8205 114 St, 3-48 Corbett Hall, Edmonton, AB Canada T6G 2G4
                [ ]Canada Research Chair in Disability Prevention and Rehabilitation, University of Ontario Institute of Technology (UOIT), 2000 Simcoe Street North, Oshawa, Ontario Canada L1H 7L7
                [ ]Faculty of Health Sciences, University of Ontario Institute of Technology (UOIT), 2000 Simcoe Street North, Oshawa, Ontario Canada L1H 7L7
                [ ]Division of Undergraduate Education, Canadian Memorial Chiropractic College, 6100 Leslie Street, Toronto, Ontario Canada M2H 3J1
                [ ]Graduate Education Program, Canadian Memorial Chiropractic College (CMCC), 6100 Leslie Street, Toronto, Ontario Canada M2H 3J1
                [ ]Rebecca MacDonald Centre for Arthritis and Autoimmune Disease, Mount Sinai Hospital, Joseph and Wolf Lebovic Health Complex, 60 Murray Street, 2nd Floor (Main), Toronto, Ontario Canada M5T 3L9
                [ ]Graduate Student, Faculty of Health Sciences, University of Ontario Institute of Technology (UOIT), 2000 Simcoe Street North, Oshawa, L1H 7L7 Ontario Canada
                [ ]Toronto Health Economics and Technology Assessment (THETA) Collaborative, 6th Floor, Room 658, 144 College Street, Toronto, Ontario Canada M5S 3M2
                [ ]Faculty of Pharmacy, University of Toronto, 144 College Street, Toronto, Ontario Canada M5S 3M2
                [ ]Institute for Work and Health, 481 University Avenue, Toronto, Ontario Canada M5G 2E9
                [ ]Departments of Orthopedic Surgery and Environmental Medicine, Occupational and Industrial Orthopedic Center, NYU School of Medicine, New York University, 550 1st Avenue, New York, NY 10016 USA
                [ ]School of Public Health and Injury Prevention Centre, University of Alberta, 3-300 Edmonton Clinic Health Academy 11405 – 87 Ave, Edmonton, Alberta Canada T6G 1C9
                Article
                89
                10.1186/s12998-016-0089-8
                4780149
                26955466
                939aa7bd-4bb8-4c26-8c08-2ef1a9ef46e9
                © Sutton et al. 2016

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 26 November 2015
                : 11 February 2016
                Funding
                Funded by: Ontario Ministry of Finance and the Financial Services Commission of Ontario
                Award ID: RFP#:OSS 00267175
                Award Recipient :
                Categories
                Reviews
                Custom metadata
                © The Author(s) 2016

                Complementary & Alternative medicine
                wrist injuries,hand injuries,carpal tunnel syndrome,review literature as topic,tennis elbow,epicondylitis,multimodal treatment

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