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      Matrices for Sensors from Inorganic, Organic, and Biological Nanocomposites

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          Abstract

          Matrices and sensors resulting from inorganic, organic and biological nanocomposites are presented in this overview. The term nanocomposite designates a solid combination of a matrix and of nanodimensional phases differing in properties from the matrix due to dissimilarities in structure and chemistry. The nanoocomposites chosen for a wide variety of health and environment sensors consist of Anodic Porous Allumina and P450scc, Carbon nanotubes and Conductive Polymers, Langmuir Blodgett Films of Lipases, Laccases, Cytochromes and Rhodopsins, Three-dimensional Nanoporous Materials and Nucleic Acid Programmable Protein Arrays.

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          Resistance of polyaniline films as a function of electrochemical potential and the fabrication of polyaniline-based microelectronic devices

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            Self-assembling protein microarrays.

            Protein microarrays provide a powerful tool for the study of protein function. However, they are not widely used, in part because of the challenges in producing proteins to spot on the arrays. We generated protein microarrays by printing complementary DNAs onto glass slides and then translating target proteins with mammalian reticulocyte lysate. Epitope tags fused to the proteins allowed them to be immobilized in situ. This obviated the need to purify proteins, avoided protein stability problems during storage, and captured sufficient protein for functional studies. We used the technology to map pairwise interactions among 29 human DNA replication initiation proteins, recapitulate the regulation of Cdt1 binding to select replication proteins, and map its geminin-binding domain.
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              Energetics, structure, mechanical and vibrational properties of single-walled carbon nanotubes

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                Author and article information

                Journal
                Materials (Basel)
                Materials (Basel)
                materials
                Materials
                MDPI
                1996-1944
                24 August 2011
                August 2011
                : 4
                : 8
                : 1483-1518
                Affiliations
                [1 ]Nanoworld Institute Fondazione ELBA Nicolini, Bergamo 24100, Italy; E-Mails: vsivo@ 123456ibf.unige.it (V.S.); rspera@ 123456ibf.unige.it (R.S); epechkova@ 123456ibf.unige.it (E.P.)
                [2 ]Chair of Biophysics, University of Genova, Genova 16121-16167, Italy; E-Mails: vbavastrello@ 123456ibf.unige.it (V.B.); tbezzerra@ 123456ibf.unige.it (T.B.); dscudieri@ 123456ibf.unige.it (D.S.)
                Author notes
                [* ]Author to whom correspondence should be addressed; E-Mail: cnicolini@ 123456ibf.unige.it .
                Article
                materials-04-01483
                10.3390/ma4081483
                5448674
                9a50e98a-8e5b-48b8-9bae-8569052c4013
                © 2011 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license ( http://creativecommons.org/licenses/by/3.0/).

                History
                : 19 May 2011
                : 02 August 2011
                : 11 August 2011
                Categories
                Review

                nanocomposite,matrix,sensors
                nanocomposite, matrix, sensors

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