Compressive strength and splitting tensile strength are both important parameters that are utilized for characterization concrete mechanical properties. This paper aims to show a possible applicability of support vector machine (SVM) to predict the splitting tensile strength of concrete from compressive strength of concrete, a SVM model was built, trained, and tested using the available experimental data gathered from the literature. All of the results predicted by the SVM model are compared with results obtained from experimental data, and we found that the predicted splitting tensile strength of concrete is in good agreement with the experimental data. The splitting tensile strength results predicted by SVM are also compared to those obtained by using empirical results of the building codes and various models. These comparisons show that SVM has strong potential as a feasible tool for predicting splitting tensile strength from compressive strength.