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      Transcriptional regulation and transformation by Myc proteins.

      Nature reviews. Molecular cell biology

      Binding Sites, Cell Transformation, Neoplastic, genetics, DNA-Binding Proteins, metabolism, Gene Expression Regulation, Neoplastic, Humans, Proto-Oncogene Proteins c-myc, Repressor Proteins, Transcription, Genetic

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          Abstract

          Myc genes are key regulators of cell proliferation, and their deregulation contributes to the genesis of most human tumours. Recently, a wealth of data has shed new light on the biochemical functions of Myc proteins and on the mechanisms through which they function in cellular transformation.

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          Journal
          16064138
          10.1038/nrm1703

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