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      OGER++: hybrid multi-type entity recognition

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          Abstract

          Background

          We present a text-mining tool for recognizing biomedical entities in scientific literature. OGER++ is a hybrid system for named entity recognition and concept recognition (linking), which combines a dictionary-based annotator with a corpus-based disambiguation component. The annotator uses an efficient look-up strategy combined with a normalization method for matching spelling variants. The disambiguation classifier is implemented as a feed-forward neural network which acts as a postfilter to the previous step.

          Results

          We evaluated the system in terms of processing speed and annotation quality. In the speed benchmarks, the OGER++ web service processes 9.7 abstracts or 0.9 full-text documents per second. On the CRAFT corpus, we achieved 71.4% and 56.7% F1 for named entity recognition and concept recognition, respectively.

          Conclusions

          Combining knowledge-based and data-driven components allows creating a system with competitive performance in biomedical text mining.

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          Most cited references30

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          Gene Ontology: tool for the unification of biology

          Genomic sequencing has made it clear that a large fraction of the genes specifying the core biological functions are shared by all eukaryotes. Knowledge of the biological role of such shared proteins in one organism can often be transferred to other organisms. The goal of the Gene Ontology Consortium is to produce a dynamic, controlled vocabulary that can be applied to all eukaryotes even as knowledge of gene and protein roles in cells is accumulating and changing. To this end, three independent ontologies accessible on the World-Wide Web (http://www.geneontology.org) are being constructed: biological process, molecular function and cellular component.
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            Uberon, an integrative multi-species anatomy ontology

            We present Uberon, an integrated cross-species ontology consisting of over 6,500 classes representing a variety of anatomical entities, organized according to traditional anatomical classification criteria. The ontology represents structures in a species-neutral way and includes extensive associations to existing species-centric anatomical ontologies, allowing integration of model organism and human data. Uberon provides a necessary bridge between anatomical structures in different taxa for cross-species inference. It uses novel methods for representing taxonomic variation, and has proved to be essential for translational phenotype analyses. Uberon is available at http://uberon.org
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              ChEBI: a database and ontology for chemical entities of biological interest

              Chemical Entities of Biological Interest (ChEBI) is a freely available dictionary of molecular entities focused on ‘small’ chemical compounds. The molecular entities in question are either natural products or synthetic products used to intervene in the processes of living organisms. Genome-encoded macromolecules (nucleic acids, proteins and peptides derived from proteins by cleavage) are not as a rule included in ChEBI. In addition to molecular entities, ChEBI contains groups (parts of molecular entities) and classes of entities. ChEBI includes an ontological classification, whereby the relationships between molecular entities or classes of entities and their parents and/or children are specified. ChEBI is available online at http://www.ebi.ac.uk/chebi/
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                Author and article information

                Contributors
                lenz.furrer@uzh.ch
                anna.jancso@uzh.ch
                colic@ifi.uzh.ch
                fabio.rinaldi@uzh.ch
                Journal
                J Cheminform
                J Cheminform
                Journal of Cheminformatics
                Springer International Publishing (Cham )
                1758-2946
                21 January 2019
                21 January 2019
                2019
                : 11
                : 7
                Affiliations
                [1 ]ISNI 0000 0004 1937 0650, GRID grid.7400.3, Institute of Computational Linguistics, , University of Zurich, ; Andreasstr. 15, 8050 Zürich, Switzerland
                [2 ]ISNI 0000 0000 9780 0901, GRID grid.11469.3b, Fondazione Bruno Kessler, ; Via Sommarive, 18, 38123 Trento, Italy
                Article
                326
                10.1186/s13321-018-0326-3
                6689863
                30666476
                9fb24136-a331-4a90-a3fc-75af4d095984
                © The Author(s) 2019

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                : 31 July 2018
                : 27 December 2018
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100001711, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung;
                Award ID: CR30I1 162758
                Award Recipient :
                Categories
                Research Article
                Custom metadata
                © The Author(s) 2019

                Chemoinformatics
                named entity recognition,concept recognition,natural language processing,machine learning

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