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      ChatGPT-4 and the Global Burden of Disease Study: Advancing Personalized Healthcare Through Artificial Intelligence in Clinical and Translational Medicine

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          Abstract

          The fusion of insights from the comprehensive global burden of disease (GBD) study and the advanced artificial intelligence of open artificial intelligence (AI) chat generative pre-trained transformer version 4 (ChatGPT-4) brings the potential to transform personalized healthcare planning. By integrating the data-driven findings of the GBD study with the powerful conversational capabilities of ChatGPT-4, healthcare professionals can devise customized healthcare plans that are adapted to patients' lifestyles and preferences. We propose that this innovative partnership can lead to the creation of a novel AI-assisted personalized disease burden (AI-PDB) assessment and planning tool.

          For the successful implementation of this unconventional technology, it is crucial to ensure continuous and accurate updates, expert supervision, and address potential biases and limitations. Healthcare professionals and stakeholders should have a balanced and dynamic approach, emphasizing interdisciplinary collaborations, data accuracy, transparency, ethical compliance, and ongoing training.

          By investing in the unique strengths of both ChatGPT-4, especially its newly introduced features such as live internet browsing or plugins, and the GBD study, we may enhance personalized healthcare planning. This innovative approach has the potential to improve patient outcomes and optimize resource utilization, as well as pave the way for the worldwide implementation of precision medicine, thereby revolutionizing the existing healthcare landscape. However, to fully harness these benefits at both the global and individual levels, further research and development are warranted. This will ensure that we effectively tap into the potential of this synergy, bringing societies closer to a future where personalized healthcare is the norm rather than the exception.

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          Most cited references5

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          ChatGPT: friend or foe?

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            Overview of Early ChatGPT’s Presence in Medical Literature: Insights From a Hybrid Literature Review by ChatGPT and Human Experts

            ChatGPT, an artificial intelligence chatbot, has rapidly gained prominence in various domains, including medical education and healthcare literature. This hybrid narrative review, conducted collaboratively by human authors and ChatGPT, aims to summarize and synthesize the current knowledge of ChatGPT in the indexed medical literature during its initial four months. A search strategy was employed in PubMed and EuropePMC databases, yielding 65 and 110 papers, respectively. These papers focused on ChatGPT's impact on medical education, scientific research, medical writing, ethical considerations, diagnostic decision-making, automation potential, and criticisms. The findings indicate a growing body of literature on ChatGPT's applications and implications in healthcare, highlighting the need for further research to assess its effectiveness and ethical concerns.
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              Enhancing Expert Panel Discussions in Pediatric Palliative Care: Innovative Scenario Development and Summarization With ChatGPT-4

              This study presents a novel approach to enhance expert panel discussions in a medical conference through the use of ChatGPT-4 (Generative Pre-trained Transformer version 4), a recently launched powerful artificial intelligence (AI) language model. We report on ChatGPT-4's ability to optimize and summarize the medical conference panel recommendations of the first Pan-Arab Pediatric Palliative Critical Care Hybrid Conference, held in Riyadh, Saudi Arabia. ChatGPT-4 was incorporated into the discussions in two sequential phases: first, scenarios were optimized by the AI model to stimulate in-depth conversations; second, the model identified, summarized, and contrasted key themes from the panel and audience discussions. The results suggest that ChatGPT-4 effectively facilitated complex do-not-resuscitate (DNR) conflict resolution by summarizing key themes such as effective communication, collaboration, patient and family-centered care, trust, and ethical considerations. The inclusion of ChatGPT-4 in pediatric palliative care panel discussions demonstrated potential benefits for enhancing critical thinking among medical professionals. Further research is warranted to validate and broaden these insights across various settings and cultures.
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                Author and article information

                Journal
                Cureus
                Cureus
                2168-8184
                Cureus
                Cureus (Palo Alto (CA) )
                2168-8184
                23 May 2023
                May 2023
                : 15
                : 5
                : e39384
                Affiliations
                [1 ] Pediatric Intensive Care Unit, Department of Pediatrics, King Saud University Medical City, College of Medicine, King Saud University, Riyadh, SAU
                [2 ] Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, SAU
                [3 ] Evidence-Based Health Care & Knowledge Translation Research Chair, Department of Family and Community Medicine, College of Medicine, King Saud University, Riyadh, SAU
                [4 ] Department of Critical Care, College of Medicine, King Saud University, Riyadh, SAU
                [5 ] Department of Specialty Internal Medicine and Quality, Johns Hopkins Aramco Healthcare, Dhahran, SAU
                [6 ] Infectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, USA
                [7 ] Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, USA
                [8 ] Pediatric Intensive Care Unit, Department of Pediatrics, College of Medicine, King Saud University, Riyadh, SAU
                [9 ] Pediatric Intensive Care Unit, King Saud University Medical City, Riyadh, SAU
                Author notes
                Mohamad-Hani Temsah temsah1@ 123456yahoo.com
                Article
                10.7759/cureus.39384
                10204616
                37223340
                a3925b9c-d1ba-429c-ae32-b91368c4b643
                Copyright © 2023, Temsah et al.

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 23 May 2023
                Categories
                Healthcare Technology
                Epidemiology/Public Health
                Health Policy

                precision medicine,personalized healthcare plan,chatbots,ai-assisted personalized disease burden,chatgpt-4,global burden of disease (gbd)

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