High‐definition transcranial direct current stimulation (HD‐tDCS) of left dorsolateral prefrontal cortex affects performance in Balloon Analogue Risk Task (BART)

Abstract

Background

Studies on risk preferences have long been of great concern and have examined the neural basis underlying risk‐based decision making. However, studies using conventional transcranial direct current stimulation ( tDCS) revealed that bilateral stimulation could change risk propensity with limited evidence of precisely focalized unilateral high‐definition transcranial direct current stimulation ( HD‐ tDCS). The aim of this experiment was to investigate the effect of HD‐ tDCS focalizing the left dorsal lateral prefrontal cortex ( DLPFC) on risk‐taking behavior during the Balloon Analogue Risk Task (BART).

Methods

This study was designed as a between‐subject, single‐blind, sham‐controlled experiment. University students were randomly assigned to three groups: the anodal group (F3 anode, AF3, F1, F5, FC3 returned), the cathodal group (F3 cathodal, AF3, F1, F5, FC3 returned) and the sham group. Subsequently, 1.5‐mA 20‐min HD‐ tDCS was applied during the BART, and the Positive Affect and Negative Affect Scale ( PANAS), the Sensation Seeking Scale‐5 ( SSS‐5), and the Behavioral Inhibition System and Behavioral Approach System scale ( BIS/ BAS) were measured as control variables.

Results

The cathodal group earned less total money than the sham group, and no significant difference was observed between the anodal group and the sham group.

Conclusions

These results showed that, to some extent, focalized unilateral cathodal HD‐ tDCS on left DLPFC could change performance during risky tasks and diminish risky decision making. Further studies are needed to investigate the dose effect and electrode distribution of HD‐ tDCS during risky tasks and examine synchronous brain activity to show the neural basis.