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      Multifunctional wettability patterns prepared by laser processing on superhydrophobic TiO2 nanostructured surfaces

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          Abstract

          An ultrafast laser technique is developed to construct a three-dimensional pattern with high wettability contrast on a superhydrophobic TiO 2 nanotube array surface for droplet manipulation and biomedical scaffold.

          Abstract

          A novel femtosecond laser patterning technique is reported to construct a three-dimensional (3D) wettability pattern on a superhydrophobic TiO 2 nanotube array (TNA) surface in one-step. A 3D binary TNA pattern with extremely high contrast for microfluidic manipulators and biomedical scaffolds is used to guide droplet transportation and human mesenchymal stem cell site-selective growth, respectively.

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          Most cited references39

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          Ti based biomaterials, the ultimate choice for orthopaedic implants – A review

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            Characterization and Distribution of Water-repellent, Self-cleaning Plant Surfaces

            C Neinhuis (1997)
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              Stem cell fate dictated solely by altered nanotube dimension.

              Two important goals in stem cell research are to control the cell proliferation without differentiation and to direct the differentiation into a specific cell lineage when desired. Here, we demonstrate such paths by controlling only the nanotopography of culture substrates. Altering the dimensions of nanotubular-shaped titanium oxide surface structures independently allowed either augmented human mesenchymal stem cell (hMSC) adhesion or a specific differentiation of hMSCs into osteoblasts by using only the geometric cues, absent of osteogenic inducing media. hMSC behavior in response to defined nanotube sizes revealed a very dramatic change in hMSC behavior in a relatively narrow range of nanotube dimensions. Small (approximately 30-nm diameter) nanotubes promoted adhesion without noticeable differentiation, whereas larger (approximately 70- to 100-nm diameter) nanotubes elicited a dramatic stem cell elongation (approximately 10-fold increased), which induced cytoskeletal stress and selective differentiation into osteoblast-like cells, offering a promising nanotechnology-based route for unique orthopedics-related hMSC treatments.
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                Author and article information

                Journal
                JMCBDV
                Journal of Materials Chemistry B
                J. Mater. Chem. B
                Royal Society of Chemistry (RSC)
                2050-750X
                2050-7518
                2015
                2015
                : 3
                : 3
                : 342-347
                Affiliations
                [1 ]School of Materials Science and Engineering
                [2 ]Nanyang Technological University
                [3 ]639798 Singapore
                [4 ]Singapore
                [5 ]National Engineering Laboratory for Modern Silk
                [6 ]College of Textile and Clothing Engineering
                [7 ]Soochow University
                [8 ]Suzhou 215123
                [9 ]P. R. China
                [10 ]Institute of Orthopaedics and Department of Orthopaedic Surgery of First Affiliated Hospital
                [11 ]Suzhou 215006
                [12 ]Singapore Institute of Manufacturing Technology
                Article
                10.1039/C4TB01814A
                aed450f8-58a9-474f-be4d-d1251d7b0253
                © 2015
                History

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