Smoking has a negative impact on skin health. Numerous studies have effectively linked smoking with delayed wound healing and healing complications. Research has identified cigarette smoking affects wound healing at a cellular level. Reducing fibroblast activity and keratinocyte migration. Such is the concern around the affects that smoking has on wound healing that some question whether smoking abstinence should be a pre requisite before some surgical procedures. This article will discuss current research and clinical studies that have investigated impaired wound healing as a result of cigarette smoking.