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      An economical in-class sticker microfluidic activity develops student expertise in microscale physics and device manufacturing†

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          Abstract

          Educating new students in miniaturization science remains challenging due to the non-intuitive behavior of microscale objects and specialized layer-by-layer assembly approaches. In our analysis of the existing literature, we noted that it remains difficult to have low cost activities that elicit deep learning. Furthermore, few activities have stated learning goals and measurements of effectiveness. To that end, we created a new educational activity that enables students to build and test microfluidic mixers, valves, and bubble generators in the classroom setting with inexpensive, widely-available materials. Although undergraduate and graduate engineering students are able to successfully construct the devices, our activity is unique in that the focus is not on successfully building and operating each device. Instead, it is to gain understanding about miniaturization science, device design, and construction so as to be able to do so independently. Our data show that the activity is appropriate for developing the conceptual understanding of graduate and advanced undergraduate students ( n = 57), as well as makes a lasting impression on the students. We also report on observations related to student patterns of misunderstanding and how miniaturization science provides a unique opportunity for educational researchers to elicit and study misconceptions. More broadly, since this activity teaches participants a viable approach to creating microsystems and can be implemented in nearly any global setting, our work democratizes the education of miniaturization science. Noting the broad potential of point-of-care technologies in the global setting, such an activity could empower local experts to address their needs.

          Abstract

          This activity enables students to construct geometrically complex microfluidics at their desk with no specialized equipment. It can be easily transported, and helped students significantly improve their understanding of miniaturization science.

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          Most cited references55

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          Formation of dispersions using “flow focusing” in microchannels

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            Patterning surfaces with functional polymers.

            The ability to pattern functional polymers at different length scales is important for research fields including cell biology, tissue engineering and medicinal science and the development of optics and electronics. The interest and capabilities of polymer patterning have originated from the abundance of functionalities of polymers and a wide range of applications of the patterns. This paper reviews recent advances in top-down and bottom-up patterning of polymers using photolithography, printing techniques, self-assembly of block copolymers and instability-induced patterning. Finally, challenges and future directions are discussed from the point of view of both applicability and strategies for the surface patterning of polymers.
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              Commonsense Conceptions of Emergent Processes: Why Some Misconceptions Are Robust

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                Author and article information

                Journal
                Lab Chip
                Lab Chip
                LC
                LCAHAM
                Lab on a Chip
                The Royal Society of Chemistry
                1473-0197
                1473-0189
                8 February 2024
                16 April 2024
                8 February 2024
                : 24
                : 8
                : 2176-2192
                Affiliations
                [a ] The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University Atlanta GA USA todd.fernandez@ 123456gatech.edu david.myers@ 123456emory.edu
                [b ] Department of Pediatrics, Division of Pediatric Haematology/Oncology, Aflac Cancer Center and Blood Disorders Service of Children's Healthcare of Atlanta, Emory University School of Medicine Atlanta GA USA
                [c ] Parker H. Petit Institute of Bioengineering and Bioscience, Georgia Institute of Technology Atlanta GA USA
                [d ] Department of Medicine, Division of Infectious Diseases, Emory University Atlanta GA USA
                [e ] Department of Global Health, Rollins School of Public Health Atlanta GA USA
                Author information
                https://orcid.org/0000-0002-2550-5051
                https://orcid.org/0000-0001-9659-3274
                Article
                d3lc00912b
                10.1039/d3lc00912b
                11019833
                38328814
                bef56690-27cf-4f73-92de-c9cc7659c888
                This journal is © The Royal Society of Chemistry
                History
                : 23 October 2023
                : 26 January 2024
                Page count
                Pages: 17
                Funding
                Funded by: National Heart, Lung, and Blood Institute, doi 10.13039/100000050;
                Award ID: 5K25HL141636-05
                Award ID: 5R01HL155330-03
                Award ID: F31HL160210-01
                Categories
                Chemistry
                Custom metadata
                Paginated Article

                Bioinformatics & Computational biology
                Bioinformatics & Computational biology

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