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      Efficacy of Intra-articular Platelet-Rich Plasma Injections in Knee Osteoarthritis: A Systematic Review.

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          Abstract

          To determine (1) whether platelet-rich plasma (PRP) injection significantly improves validated patient-reported outcomes in patients with symptomatic knee osteoarthritis (OA) at 6 and 12 months postinjection, (2) differences in outcomes between PRP and corticosteroid injections or viscosupplementation or placebo injections at 6 and 12 months postinjection, and (3) similarities and differences in outcomes based on the PRP formulations used in the analyzed studies.

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          Author and article information

          Journal
          Arthroscopy
          Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association
          1526-3231
          0749-8063
          Mar 2016
          : 32
          : 3
          Affiliations
          [1 ] Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, Texas, U.S.A.
          [2 ] Department of Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, Texas, U.S.A.. Electronic address: joshuaharrismd@gmail.com.
          Article
          S0749-8063(15)00659-3
          10.1016/j.arthro.2015.08.005
          26432430
          c135988c-ae4e-42ef-92c5-7914e379372a
          Copyright © 2016 Arthroscopy Association of North America. Published by Elsevier Inc. All rights reserved.
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