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      Call for Papers: Green Renal Replacement Therapy: Caring for the Environment

      Submit here before September 30, 2024

      About Blood Purification: 3.0 Impact Factor I 5.6 CiteScore I 0.83 Scimago Journal & Country Rank (SJR)

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      Counselling Prior to Blood-Borne Virus Screening in Haemodialysis Patients: A Survey of Patient Experience and Opinion

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          Abstract

          Background: Patients with end-stage renal disease receiving renal replacement therapy are at higher risk of infection with hepatitis B, C and HIV viruses as compared to the general population. Early screening, education and vaccination potentially reduce the risk of acquiring these viruses and therefore future morbidity and mortality. We have sought to establish the opinions, perceptions and understanding of patients regarding the routine testing for blood-borne viruses (BBV) to help improve testing strategies. Methods: An anonymised survey was conducted in all local dialysis patients that asked their understanding, knowledge and opinions on BBV screening and counselling. Results: 55.3% (167/302) of all local dialysis patients responded to the survey. 55.1% of these patients knew that they had been screened for BBV and only 12.6% indicated that they had received any counselling prior to testing. However, 74.3% answered that they would be happy to be tested without consent or counselling. Conclusion: The majority of the patients had not received adequate information regarding BBV screening, but most were content with regular viral screening after initial counselling and consent. Information during pre-dialysis sessions may be an appropriate way of educating patients about the importance of BBV.

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          Patterns of hepatitis B prevalence and seroconversion in hemodialysis units from three continents: the DOPPS.

          Robert Port, John R LaBrecque, Christian Combe … (2003)
          Hepatitis B (HBV) historically has been a public health issue within hemodialysis units. This study estimates HBV prevalence and seroconversion rates across seven countries and investigates associations with facility level practice patterns. The study sample was from the Dialysis Outcomes and Practice Patterns Study (DOPPS), a cross-sectional, prospective, observational study of adult hemodialysis patients randomly selected from 308 dialysis facilities in France, Germany, Italy, Spain, the United Kingdom, Japan, and the United States. Logistic regression was used to model the odds ratio (OR) of HBV prevalence, and Cox regression was used to model time from entry into the study to HBV seroconversion. In this sample, mean HBV facility prevalence was 3.0% with a median of 1.9%. The percentage of facilities with an HBV prevalence 0% to 5% was 78.5%. Adjusted HBV prevalence was higher in France, Germany, and Italy and lower in Japan and the United Kingdom. The majority of facilities (78.1%) had a seroconversion rate of 0 conversions per 100 patient-years. Presence of a protocol for HBV-infected patients was significantly associated with HBV seroconversion in the separate practice pattern model [risk ratio (RR) = 0.52, P = 0.03] and in the combined practice pattern model (RR = 0.44, P = 0.01). There are differences in HBV prevalence and rate of seroconversion both at the country and the hemodialysis facility level. Presence of a protocol for HBV-infected patients was strongly and significantly associated with decreased risk for seroconversion. The observed variation suggests opportunities for improved HBV outcomes with further definition of optimal practice patterns at the facility level.
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            Nosocomial transmission of hepatitis C virus within a British dialysis centre.

            Joseph K. McLaughlin, Wendy Davidson, David J. P. Ferguson … (1997)
            Patients on renal replacement therapy are recognized as a group at increased risk of infection with hepatitis C virus (HCV). While the risk has been reduced by the use of erythropoietin for treatment of anaemia and the introduction of HCV screening of blood products and potential renal transplant donors, new cases of HCV are still being documented, with patients on hospital haemodialysis appearing to be particularly at risk. The exact mode of transmission of HCV within dialysis units is unclear, although there is evidence to support nosocomial transmission between patients. Third generation HCV antibody testing was performed on all dialysis patients when a new case of HCV was identified within our unit. Stored monthly serum samples were then examined retrospectively to determine when patients became HCV RNA and HCV antibody positive. Viral typing was carried out to identify the HCV strains responsible for transmission. Four new cases of HCV infection are described within a single dialysis shift. Viral typing identified two distinct strains of HCV as being responsible for these infections, both of which had previously been identified in dialysis patients within the unit known to have HCV infection. This information, taken in conjunction with knowledge of the location of each patient for dialysis, suggests two separate episodes of nosocomial transmission of HCV between haemodialysis patients. While evidence of nosocomial transmission of HCV is accumulating, with modern dialytic procedures evidence of transmission through the dialysis machine or equipment used for dialysis is lacking. This stresses the importance of strict applications of universal precautions as the key to prevention of further transmission of HCV infection. This information is obviously applicable not only to dialysis units but all units that may potentially come in contact with HCV patients.
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              Epidemiology and mechanisms of transmission of the hepatitis C virus in haemodialysis.

              M Jadoul (2000)
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                Author and article information

                Journal
                Journal ID (publisher-id): NEC
                Journal ID (nlm-ta): Nephron Clin Pract
                Journal ID (doi): 10.1159/issn.1660-2110
                Title: Nephron Clinical Practice
                Publisher: S. Karger AG
                ISSN (Electronic): 1660-2110
                Publication date Subscription-year: 2009
                Publication date (Print): May 2009
                Publication date (Electronic): 18 April 2009
                Volume: 112
                Issue: 2
                Pages: c94-c97
                Affiliations
                Department of Renal Medicine, Hull and East Yorkshire Hospitals NHS Trust and Hull York Medical School, Hull Royal Infirmary, Kingston upon Hull, UK
                Article
                Publisher ID: 213087 Other ID: Nephron Clin Pract 2009;112:c94–c97
                DOI: 10.1159/000213087
                PubMed ID: 19390208
                SO-VID: c85ea77b-2aa8-40a1-8e53-da4c342c04ae
                Copyright © © 2009 S. Karger AG, Basel
                License:

                Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

                History
                Date received : 09 October 2008
                Date accepted : 12 December 2008
                Page count
                Tables: 3, References: 13, Pages: 1
                Categories
                Subject: Original Paper

                ScienceOpen disciplines: Cardiovascular Medicine,Nephrology
                Keywords: End-stage renal disease,Renal replacement therapy,Counselling,Blood-borne viruses,Hepatitis
                Data availability:
                ScienceOpen disciplines: Cardiovascular Medicine, Nephrology
                Keywords: End-stage renal disease, Renal replacement therapy, Counselling, Blood-borne viruses, Hepatitis

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