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      Aerobic interval training and continuous training equally improve aerobic exercise capacity in patients with coronary artery disease: the SAINTEX-CAD study.

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          Abstract

          Exercise-based cardiac rehabilitation increases peak oxygen uptake (peak VO₂), which is an important predictor of mortality in cardiac patients. However, it remains unclear which exercise characteristics are most effective for improving peak VO₂ in coronary artery disease (CAD) patients. Proof of concept papers comparing Aerobic Interval Training (AIT) and Moderate Continuous Training (MCT) were conducted in small sample sizes and findings were inconsistent and heterogeneous. Therefore, we aimed to compare the effects of AIT and Aerobic Continuous Training (ACT) on peak VO₂, peripheral endothelial function, cardiovascular risk factors, quality of life and safety, in a large multicentre study.

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          Author and article information

          Journal
          Int. J. Cardiol.
          International journal of cardiology
          1874-1754
          0167-5273
          Jan 20 2015
          : 179
          Affiliations
          [1 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; University of Antwerp, Antwerp, Belgium.
          [2 ] Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium. Electronic address: nele.pattyn@faber.kuleuven.be.
          [3 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; University of Antwerp, Antwerp, Belgium. Electronic address: catherine.demaeyer@uza.be.
          [4 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; University of Antwerp, Antwerp, Belgium. Electronic address: paul.beckers@uza.be.
          [5 ] Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium. Electronic address: ellen.coeckelberghs@faber.kuleuven.be.
          [6 ] Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium. Electronic address: veronique.cornelissen@faber.kuleuven.be.
          [7 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; CoRPS-Centre of Research on Psychology in Somatic diseases, Tilburg University, Tilburg, The Netherlands. Electronic address: j.denollet@uvt.nl.
          [8 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; Laboratory of Cellular and Molecular Cardiology, Antwerp University Hospital, Edegem, Belgium. Electronic address: geert.frederix@uza.be.
          [9 ] Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; Department of Cardiovascular Diseases, University Hospitals of Leuven, Leuven, Belgium. Electronic address: kaatje.goetschalckx@uzleuven.be.
          [10 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; University of Antwerp, Antwerp, Belgium; Laboratory of Cellular and Molecular Cardiology, Antwerp University Hospital, Edegem, Belgium. Electronic address: vicky.hoymans@uza.be.
          [11 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium. Electronic address: nadine.possemiers@uza.be.
          [12 ] Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium. Electronic address: dirk.schepers@uzleuven.be.
          [13 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; University of Antwerp, Antwerp, Belgium. Electronic address: bharati.shivalkar@uza.be.
          [14 ] Department of Cardiovascular Diseases, University Hospitals of Leuven, Leuven, Belgium. Electronic address: jens.uwe.voigt@gmx.net.
          [15 ] Department of Cardiology, Antwerp University Hospital, Edegem, Belgium; University of Antwerp, Antwerp, Belgium; Laboratory of Cellular and Molecular Cardiology, Antwerp University Hospital, Edegem, Belgium. Electronic address: emeline.vancraenenbroeck@uantwerpen.be.
          [16 ] Department of Rehabilitation Sciences, KU Leuven, Leuven, Belgium; Department of Cardiovascular Diseases, University Hospitals of Leuven, Leuven, Belgium. Electronic address: luc.vanhees@faber.kuleuven.be.
          Article
          S0167-5273(14)02092-0
          10.1016/j.ijcard.2014.10.155
          25464446
          d219cbb3-d32e-49c9-9e8b-a065befb5f17
          Copyright © 2014. Published by Elsevier Ireland Ltd.
          History

          Cardiac rehabilitation,Coronary artery disease,Endothelial function,Exercise intensity,Secondary prevention,Training modality

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