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Effect of phase-encoding direction on group analysis of resting-state functional magnetic resonance imaging : Phase-encoding direction affects rsfMRI
Yasuo Mori
1 ,
Jun Miyata
1 ,
Masanori Isobe
1 ,
Shuraku Son
1 ,
Yujiro Yoshihara
1
,
2 ,
Toshihiko Aso
1 ,
Takanori Kouchiyama
3 ,
Toshiya Murai
1 ,
Hidehiko Takahashi
1
July 02 2018
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Abstract
Echo-planar imaging is a common technique used in functional magnetic resonance imaging
(fMRI); however, it suffers from image distortion and signal loss because of large
susceptibility effects that are related to the phase-encoding direction of the scan.
Despite this relation, the majority of neuroimaging studies has not considered the
influence of phase-encoding direction. Here, we aimed to clarify how phase-encoding
direction can affect the outcome of an fMRI connectivity study of schizophrenia (SCZ).