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Complete genome sequence of a tenth human polyomavirus.

Author(s): K. H. McDermott, Giao Phan, Manish Raiji, Philip M Murphy, Michael P. Murphy, Alison A. McBride

Publication date: 2012-09-30

Keywords: DNA Replication, DNA Restriction Enzymes, metabolism, Genome, Viral, Humans, Immunologic Deficiency Syndromes, virology, Molecular Sequence Data, Polyomavirus, genetics, Sequence Analysis, DNA, Skin, Virus Replication, Warts

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Abstract

Nine polyomavirus (PyV) species are known to productively infect humans. The circular DNA genomes of PyVs are readily detectable using rolling circle amplification (RCA). RCA-based analysis of condyloma specimens from a patient with warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome demonstrated the presence of a tenth apparently human-tropic polyomavirus species, which we name HPyV10.

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PubMed ID:: 22966183

PMC ID:: 3457262

DOI:: 10.1128/JVI.01690-12

ScienceOpen disciplines: Chemistry

Keywords: DNA Replication,DNA Restriction Enzymes,metabolism,Genome, Viral,Humans,Immunologic Deficiency Syndromes,virology,Molecular Sequence Data,Polyomavirus,genetics,Sequence Analysis, DNA,Skin,Virus Replication,Warts

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ScienceOpen disciplines: Chemistry

Complete genome sequence of a tenth human polyomavirus.

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