Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS One
Journal ID (publisher-id): plos
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, CA USA
)
ISSN
(Electronic):
1932-6203
Publication date
(Electronic):
9
September
2022
Publication date Collection: 2022
Volume: 17
Issue: 9
Electronic Location Identifier: e0272529
Affiliations
[1
]
Department of Industrial Engineering, Alma Mater Studiorum—University of Bologna,
Bologna, Italy
[2
]
Medical Technology Lab, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy
Medical College of Wisconsin, UNITED STATES
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Author information
Article
Publisher ID:
PONE-D-22-01308
DOI: 10.1371/journal.pone.0272529
PMC ID: 9462677
PubMed ID: 36084092
SO-VID: db784854-d121-4e8a-acc8-a068f28f619b
Copyright © © 2022 Garavelli et al
License:
This is an open access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
Funded by:
funder-id http://dx.doi.org/10.13039/501100007601, Horizon 2020;
Award ID: 823712
Award Recipient
:
Marco Viceconti
Funded by:
funder-id http://dx.doi.org/10.13039/501100007601, Horizon 2020;
Award ID: 101016503
Award Recipient
:
Marco Viceconti
Funded by:
funder-id http://dx.doi.org/10.13039/100010665, H2020 Marie Skłodowska-Curie Actions;
Award ID: 832430
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1231-2728
Marco Palanca
Funded by:
funder-id http://dx.doi.org/10.13039/501100001702, AO Foundation;
Award ID: AOSDIA 2019_063_TUM_Palanca
Award Recipient
:
ORCID: https://orcid.org/0000-0002-1231-2728
Marco Palanca
Funded by:
Re-use with Love
Award Recipient
:
ORCID: https://orcid.org/0000-0002-7473-6868
Luca Cristofolini
Funded by:
funder-id http://dx.doi.org/10.13039/501100007601, Horizon 2020;
Award ID: 823712
Award Recipient
:
ORCID: https://orcid.org/0000-0002-6921-0730
Chiara Garavelli
CG, MV: H2020 project “CompBioMed2: A Centre of Excellence in Computational Biomedicine”
(topic INFRAEDI-02-2018, grant ID 823712, URL:
https://www.compbiomed.eu/). MV: H2020 project “In Silico World: Lowering barriers to ubiquitous adoption of
In Silico Trials” (topic SC1-DTH-06-2020, grant ID 101016503, URL:
https://insilico.world/). MP: Marie Skłodowska-Curie Individual Fellowship (MetaSpine, MSCA-IF-EF-ST, 832430/2018,
URL:
https://ec.europa.eu/research/mariecurieactions/), the AOSpine Discovery and Innovation Awards (AOSDIA 2019_063_TUM_Palanca, URL:
https://aospine.aofoundation.org/about-aospine/news/2019/2019_04-winners-2019-discovery-and-innovation-awards). LC: “Re-use with Love” (research grant year 2019, URL:
https://www.reusewithlove.org/it/home/). The funders had no role in study design, data collection and analysis, decision
to publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Musculoskeletal System
Subject:
Skeleton
Subject:
Spine
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Musculoskeletal System
Subject:
Skeleton
Subject:
Spine
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Musculoskeletal System
Subject:
Skeleton
Subject:
Spine
Subject:
Vertebrae
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Musculoskeletal System
Subject:
Skeleton
Subject:
Spine
Subject:
Vertebrae
Subject:
Medicine and Health Sciences
Subject:
Critical Care and Emergency Medicine
Subject:
Trauma Medicine
Subject:
Traumatic Injury
Subject:
Bone Fracture
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Musculoskeletal System
Subject:
Skeleton
Subject:
Bone
Subject:
Bone Density
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Musculoskeletal System
Subject:
Skeleton
Subject:
Bone
Subject:
Bone Density
Subject:
Biology and Life Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Bone
Subject:
Bone Density
Subject:
Medicine and Health Sciences
Subject:
Anatomy
Subject:
Biological Tissue
Subject:
Connective Tissue
Subject:
Bone
Subject:
Bone Density
Subject:
Medicine and Health Sciences
Subject:
Oncology
Subject:
Cancers and Neoplasms
Subject:
Neurological Tumors
Subject:
Spinal Metastasis
Subject:
Medicine and Health Sciences
Subject:
Neurology
Subject:
Neurological Tumors
Subject:
Spinal Metastasis
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Neuroimaging
Subject:
Computed Axial Tomography
Subject:
Biology and Life Sciences
Subject:
Neuroscience
Subject:
Neuroimaging
Subject:
Computed Axial Tomography
Subject:
Medicine and Health Sciences
Subject:
Diagnostic Medicine
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Computed Axial Tomography
Subject:
Research and Analysis Methods
Subject:
Imaging Techniques
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Computed Axial Tomography
Subject:
Medicine and Health Sciences
Subject:
Radiology and Imaging
Subject:
Diagnostic Radiology
Subject:
Tomography
Subject:
Computed Axial Tomography
Subject:
Medicine and Health Sciences
Subject:
Epidemiology
Subject:
Medical Risk Factors
Subject:
Traumatic Injury Risk Factors
Subject:
Medicine and Health Sciences
Subject:
Public and Occupational Health
Subject:
Traumatic Injury Risk Factors
Subject:
Physical Sciences
Subject:
Mathematics
Subject:
Applied Mathematics
Subject:
Finite Element Analysis