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      Benchmark of Deep Learning Models on Large Healthcare MIMIC Datasets

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          Abstract

          Deep learning models (aka Deep Neural Networks) have revolutionized many fields including computer vision, natural language processing, speech recognition, and is being increasingly used in clinical healthcare applications. However, few works exist which have benchmarked the performance of the deep learning models with respect to the state-of-the-art machine learning models and prognostic scoring systems on publicly available healthcare datasets. In this paper, we present the benchmarking results for several clinical prediction tasks such as mortality prediction, length of stay prediction, and ICD-9 code group prediction using Deep Learning models, ensemble of machine learning models (Super Learner algorithm), SAPS II and SOFA scores. We used the Medical Information Mart for Intensive Care III (MIMIC-III) (v1.4) publicly available dataset, which includes all patients admitted to an ICU at the Beth Israel Deaconess Medical Center from 2001 to 2012, for the benchmarking tasks. Our results show that deep learning models consistently outperform all the other approaches especially when the `raw' clinical time series data is used as input features to the models.

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          Multilayer feedforward networks are universal approximators

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            APACHE-acute physiology and chronic health evaluation: a physiologically based classification system.

            Investigations describing the utilization pattern and documenting the value of intensive care are limited by the lack of a reliable and valid classification system. In this paper, the authors describe the development and initial validation of acute physiology and chronic health evaluation (APACHE), a physiologically based classification system for measuring severity of illness in groups of critically ill patients. APACHE uses information available in the medical record. In studies on 582 admissions to a university hospital ICU and 223 admissions to a community hospital ICU, APACHE was reliable in classifying ICU admissions. In validation studies involving these 805 admissions, the acute physiology score of APACHE demonstrated consistent agreement with subsequent therapeutic effort and mortality. This was true for a broad range of patient groups using a variety of sensitivity analyses. After successful completion of multi-institutional validation studies, the APACHE classification system could be used to control for case mix, compare outcomes, evaluate new therapies, and study the utilization of ICUs.
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              Context-Dependent Pre-Trained Deep Neural Networks for Large-Vocabulary Speech Recognition

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                Author and article information

                Journal
                23 October 2017
                Article
                1710.08531
                e6b62a2b-096b-4d30-88db-f61ba3e7b7d5

                http://arxiv.org/licenses/nonexclusive-distrib/1.0/

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                Custom metadata
                Submitted to Journal of Biomedical Informatics (JBI). First two authors have equal contributions
                cs.LG cs.CY stat.ML

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