Journal ID (nlm-ta): PLoS One
Journal ID (iso-abbrev): PLoS ONE
Journal ID (publisher-id): plos
Journal ID (pmc): plosone
Title:
PLoS ONE
Publisher:
Public Library of Science
(San Francisco, USA
)
ISSN
(Electronic):
1932-6203
Publication date Collection: 2014
Publication date
(Electronic):
11
March
2014
Volume: 9
Issue: 3
Electronic Location Identifier: e91332
Affiliations
[1]State Key Laboratory of Natural Medicines, Jiangsu Key Laboratory of Carcinogenesis
and Intervention, Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry
of Education, China Pharmaceutical University, Nanjing, People's Republic of China
Xuzhou Medical college, China
Author notes
Competing Interests: The authors have declared that no competing interests exist.
Conceived and designed the experiments: CL NL QG. Performed the experiments: CL FL
KZ YC. Analyzed the data: CL JY LZ. Contributed reagents/materials/analysis tools:
ZL. Wrote the paper: CL FL NL.
Article
Publisher ID:
PONE-D-13-44814
DOI: 10.1371/journal.pone.0091332
PMC ID: 3950212
PubMed ID: 24618693
SO-VID: e78265ad-ad09-4b1d-8957-2b4ee48022ae
Copyright statement:
Copyright @
2014
License:
This is an open-access article distributed under the terms of the
Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided
the original author and source are credited.
This work was supported by the Natural Science Foundation of China (No. 21072232),
the Project Program of State Key Laboratory of Natural Medicines, China Pharmaceutical
University (No. JKGZ201101, SKLNMZZ201210, SKLNMZZCX201303, SKLNMZZJQ201302), the
Natural Science Foundation of Jiangsu province (No. BK2011620, BK20130220), the Program
for Changjiang Scholars and Innovative Research Team in University (IRT1193), the
National Science & Technology Major Project (No. 2013ZX0 9103-001-007, 2012ZX09304-001),
the China Postdoctoral Science Foundation funded project (2013M 541733), the Jiangsu
Planned Projects for Postdoctoral Research Funds (1301015B), and the Natural Science
Foundation of the Higher Education Institutions of Jiangsu Province (13KJB350007).
The funders had no role in study design, data collection and analysis, decision to
publish, or preparation of the manuscript.
Subject:
Research Article
Subject:
Biology
Subject:
Model Organisms
Subject:
Animal Models
Subject:
Mouse
Subject:
Molecular Cell Biology
Subject:
Signal Transduction
Subject:
Signaling Cascades
Subject:
Akt Signaling Cascade
Subject:
Signaling in Selected Disciplines
Subject:
Immunological Signaling
Subject:
Medicine
Subject:
Obstetrics and Gynecology
Subject:
Breast Cancer
Subject:
Oncology
Subject:
Basic Cancer Research
Subject:
Metastasis
Subject:
Cancer Treatment
Subject:
Chemotherapy and Drug Treatment