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MicroRNA history: Discovery, recent applications, and next frontiers
December 2011
December 2011
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Abstract
Since 1993, when the first small non-coding RNA was identified, our knowledge about
microRNAs has grown exponentially. In this review, we focus on the main progress in
this field and discuss the most important findings under a historical perspective.
In addition, we examine microRNAs as markers of disease diagnosis and prognosis, and
as new therapeutic targets.
Copyright © 2011 Elsevier B.V. All rights reserved.