Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure

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Abstract

High-flow nasal oxygen therapy is increasingly used for acute hypoxemic respiratory failure (AHRF).

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Most cited references 15

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Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial.

Gonzalo Hernández, Concepción Vaquero, Paloma González-Sánchez … (2016)

Studies of mechanically ventilated critically ill patients that combine populations that are at high and low risk for reintubation suggest that conditioned high-flow nasal cannula oxygen therapy after extubation improves oxygenation compared with conventional oxygen therapy. However, conclusive data about reintubation are lacking.

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High-Flow Nasal Oxygen vs Noninvasive Positive Airway Pressure in Hypoxemic Patients After Cardiothoracic Surgery: A Randomized Clinical Trial.

François Stephan, Benoit Barrucand, Pascal Petit … (2015)

Noninvasive ventilation delivered as bilevel positive airway pressure (BiPAP) is often used to avoid reintubation and improve outcomes of patients with hypoxemia after cardiothoracic surgery. High-flow nasal oxygen therapy is increasingly used to improve oxygenation because of its ease of implementation, tolerance, and clinical effectiveness.

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Prevalence of Immunosuppression Among US Adults, 2013

Rafael Harpaz, Rebecca M Dahl, Kathleen Dooling (2016)

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Author and article information

Journal

Title: JAMA

Abbreviated Title: JAMA

Publisher: American Medical Association (AMA)

ISSN (Print): 0098-7484

Publication date Created: November 27 2018

Publication date (Print): November 27 2018

Volume: 320

Issue: 20

Page: 2099

Affiliations

[1 ]Medical Intensive Care Unit and Department of Biostatistics, APHP, Hôpital St-Louis, Paris, France.

[2 ]Intensive Care Unit, Paoli Calmettes Institut, Marseille, France

[3 ]Critical Care Center, CHU de Lille, Lille, France

[4 ]Medical Intensive Care Unit, Hospices Civils de Lyon, Hôpital Edouard Herriot, Lyon, France

[5 ]Medical Intensive Care Unit, Hôpital Cochin, APHP, Université Paris Descartes, Paris, France

[6 ]Medical Intensive Care Unit, INSERM U1088, Amiens University Hospital, Amiens, France

[7 ]Medical Intensive Care Unit, André Mignot Hospital, Versailles, France

[8 ]Medical Intensive Care Unit, CHU de Montpellier, Montpellier, France

[9 ]Medical Intensive Care Unit, La Source Hospital, CHR Orléans, Orléans, France

[10 ]Medical Intensive Care Unit, Hotel Dieu, CHU de Nantes, Nantes, France

[11 ]Intensive Care Unit, Institut Gustave Roussy, Villejuif, France

[12 ]Intensive Care Unit, CHR de Metz-Thionville, Metz, France

[13 ]Department of Perioperative Medicine, CHU Clermont-Ferrand, Clermont-Ferrand, France

[14 ]Medical Intensive Care Unit and Respiratory Division, APHP, Hôpital Pitié-Salpêtrière, Sorbonne University, Paris, France

[15 ]Intensive Care Unit, Lyon Sud Medical Center, Lyon, France

[16 ]Medical Intensive Care Unit, CHRU, Angers, France

[17 ]Intensive Care Unit, Centre Hospitalier Métropole-Savoie, Chambery, France

[18 ]Medical Intensive Care Unit, Hôpital Brabois, Vandoeuvre Les Nancy, France

[19 ]Medical Intensive Care Unit, Hôpital Charles Nicolle, Rouen, France

[20 ]Montpellier University Hospital, PhyMedExp, INSERM U-1046, CNRS 34295 Montpellier, France

[21 ]Medical Intensive Care Unit, Avicenne University Hospital, Bobigny, France

[22 ]Intensive Care Unit, Roubaix hospital, Roubaix, France

[23 ]Medical Intensive Care Unit, CHU de Grenoble Alpes, Grenoble, France

[24 ]Medical Intensive Care Unit, CHU Bichat, Paris, France

[25 ]Intensive Care Unit, Centre Hospitalier Départemental Les Oudairies, La Roche Sur Yon, France

[26 ]Medical Intensive Care Unit, Gabriel-Montpied University Hospital, Clermont-Ferrand, France

[27 ]Medical Intensive Care Unit, CHU St-Antoine, Paris, France

[28 ]Department of Anesthesia and Critical Care, Necker Hospital, Paris, France

[29 ]Réanimation des Détresses Respiratoires et Infections Sévères, Assistance Publique–Hôpitaux de Marseille, Hôpital Nord, Aix-Marseille Université, Faculté de Médecine, Marseille, France

[30 ]Respiratory Intensive Care Unit, Hôpital Cochin, Paris, France

Article

DOI: 10.1001/jama.2018.14282

PMC ID: 6583581

PubMed ID: 30357270

SO-VID: eb45164a-276a-47cb-bc71-b6adf92202d6

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Effect of High-Flow Nasal Oxygen vs Standard Oxygen on 28-Day Mortality in Immunocompromised Patients With Acute Respiratory Failure : The HIGH Randomized Clinical Trial

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Abstract

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JAMA Network: Coronavirus

Most cited references 15

Effect of Postextubation High-Flow Nasal Cannula vs Conventional Oxygen Therapy on Reintubation in Low-Risk Patients: A Randomized Clinical Trial.

High-Flow Nasal Oxygen vs Noninvasive Positive Airway Pressure in Hypoxemic Patients After Cardiothoracic Surgery: A Randomized Clinical Trial.

Prevalence of Immunosuppression Among US Adults, 2013

Author and article information

Journal

Affiliations

Article

History

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Cited by 95

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