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Downregulation of DLGAP1-Antisense RNA 1 Alleviates Vascular Endothelial Cell Injury Via Activation of the Phosphoinositide 3-kinase/Akt Pathway Results from an Acute Limb Ischemia Rat Model
Guang-Hui Shen ,
Ye Song ,
Ye Yao ,
Qing-Feng Sun ,
Bao Jing ,
Jia Wu ,
Shi-Yong Li ,
Si-Qi Liu ,
Hao-Cheng Li ,
Chao Yuan ,
Gao-Yan Liu ,
Jing-Bo Li ,
Xin-Yu Liu ,
Hai-Yang Wang
November 2019
November 2019
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Abstract
This study aimed to investigate the effect of long non-coding RNA (lncRNA) DLGAP1
antisense RNA 1 (DLGAP1-AS1) on vascular endothelial cell (VEC) injury via the phosphoinositide
3-kinase (PI3K)/Akt pathway in rat models of acute lower limb ischaemia-reperfusion
(I/R).