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      The second wave of synthetic biology: from modules to systems.

      Nature reviews. Molecular cell biology

      Software, Nanotechnology, Models, Biological, Humans, Genome, Gene Regulatory Networks, Gene Expression Regulation, Epigenesis, Genetic, methods, Engineering, Computer Simulation, Cell Line, Biotechnology, Biology, metabolism, genetics, Bacteria

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          Abstract

          Synthetic biology is a research field that combines the investigative nature of biology with the constructive nature of engineering. Efforts in synthetic biology have largely focused on the creation and perfection of genetic devices and small modules that are constructed from these devices. But to view cells as true 'programmable' entities, it is now essential to develop effective strategies for assembling devices and modules into intricate, customizable larger scale systems. The ability to create such systems will result in innovative approaches to a wide range of applications, such as bioremediation, sustainable energy production and biomedical therapies.

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          Journal
          10.1038/nrm2698
          19461664

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