Histological Subtypes of Hepatocellular Carcinoma Are Related To Gene Mutations and Molecular Tumour Classification.

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Abstract

Our increasing understanding of hepatocellular carcinoma (HCC) biology holds promise for personalized care, however its translation into clinical practice requires a precise knowledge of its relationship to tumour phenotype.

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Journal

Journal ID (iso-abbrev): J. Hepatol.

Title: Journal of hepatology

Publisher: Elsevier BV

ISSN (Electronic): 1600-0641

ISSN (Print): 0168-8278

Publication date (Electronic): May 19 2017

Affiliations

[1 ] Inserm, UMR-1162, Functional Genomics of Solid Tumors, Equipe Labellisée Ligue Contre le Cancer, Université Paris Descartes, Université Paris Diderot, Université Paris 13, France., F-75010, France; Assistance Publique-Hôpitaux de Paris, Department of Pathology, CHU Henri Mondor, Créteil, France; Université Paris Est Créteil, Faculté de Médecine, Créteil, France.

[2 ] Inserm, UMR-1162, Functional Genomics of Solid Tumors, Equipe Labellisée Ligue Contre le Cancer, Université Paris Descartes, Université Paris Diderot, Université Paris 13, France., F-75010, France.

[3 ] Université Paris Est Créteil, Faculté de Médecine, Créteil, France; Assistance Publique-Hôpitaux de Paris, Department of Hepatology, CHU Henri Mondor, Créteil, France; Inserm U955, Team 18, Créteil, France.

[4 ] Department of Hepatogastroenterology and digestive oncology, CHU Bordeaux, Hôpital Haut-Lévêque, 33600, Pessac; Inserm UMR 1053, Université de Bordeaux, 33076 Bordeaux, France.

[5 ] Department of Digestive and Endocrine Surgery, CHU-Hôpitaux de Bordeaux, France.

[6 ] Université Paris Est Créteil, Faculté de Médecine, Créteil, France; Department of Digestive and Hepatobiliary Surgery, Assistance Publique-Hôpitaux de Paris, Centre Hospitalier Universitaire Henri Mondor, 94000 Créteil, France.

[7 ] Inserm UMR 1053, Université de Bordeaux, 33076 Bordeaux, France; Department of Pathology, Pellegrin Hospital, CHU Bordeaux, Bordeaux 33076, France.

[8 ] Inserm, UMR-1162, Functional Genomics of Solid Tumors, Equipe Labellisée Ligue Contre le Cancer, Université Paris Descartes, Université Paris Diderot, Université Paris 13, France., F-75010, France; Liver unit, Hôpital Jean Verdier, Hôpitaux Universitaires Paris-Seine-Saint-Denis, Assistance-Publique Hôpitaux de Paris, Bondy, France.

[9 ] Inserm, UMR-1162, Functional Genomics of Solid Tumors, Equipe Labellisée Ligue Contre le Cancer, Université Paris Descartes, Université Paris Diderot, Université Paris 13, France., F-75010, France; Assistance Publique-Hôpitaux de Paris, Department of Oncology, Hopital Européen Georges Pompidou, Paris, France. Electronic address: jessica.zucman-rossi@inserm.fr.

Article

Publisher Item ID: S0168-8278(17)32050-0

DOI: 10.1016/j.jhep.2017.05.014

PubMed ID: 28532995

SO-VID: f43f8d60-100b-480c-b607-ad9325d665da

History

Keywords: Hepatocellular carcinoma,Histopathology,Molecular carcinogenesis,Mutations

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Keywords: Hepatocellular carcinoma, Histopathology, Molecular carcinogenesis, Mutations

Histological Subtypes of Hepatocellular Carcinoma Are Related To Gene Mutations and Molecular Tumour Classification.

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