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      Endogenous Endophthalmitis - A Major Review

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          Occurrence of the potent mutagens 2- nitrobenzanthrone and 3-nitrobenzanthrone in fine airborne particles

          Polycyclic aromatic compounds (PACs) are known due to their mutagenic activity. Among them, 2-nitrobenzanthrone (2-NBA) and 3-nitrobenzanthrone (3-NBA) are considered as two of the most potent mutagens found in atmospheric particles. In the present study 2-NBA, 3-NBA and selected PAHs and Nitro-PAHs were determined in fine particle samples (PM 2.5) collected in a bus station and an outdoor site. The fuel used by buses was a diesel-biodiesel (96:4) blend and light-duty vehicles run with any ethanol-to-gasoline proportion. The concentrations of 2-NBA and 3-NBA were, on average, under 14.8 µg g−1 and 4.39 µg g−1, respectively. In order to access the main sources and formation routes of these compounds, we performed ternary correlations and multivariate statistical analyses. The main sources for the studied compounds in the bus station were diesel/biodiesel exhaust followed by floor resuspension. In the coastal site, vehicular emission, photochemical formation and wood combustion were the main sources for 2-NBA and 3-NBA as well as the other PACs. Incremental lifetime cancer risk (ILCR) were calculated for both places, which presented low values, showing low cancer risk incidence although the ILCR values for the bus station were around 2.5 times higher than the ILCR from the coastal site.
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            Clinical Practice Guideline for the Management of Candidiasis: 2016 Update by the Infectious Diseases Society of America.

            It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.
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              Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America.

              It is important to realize that guidelines cannot always account for individual variation among patients. They are not intended to supplant physician judgment with respect to particular patients or special clinical situations. IDSA considers adherence to these guidelines to be voluntary, with the ultimate determination regarding their application to be made by the physician in the light of each patient's individual circumstances.
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                Author and article information

                Contributors
                Journal
                Ocular Immunology and Inflammation
                Ocular Immunology and Inflammation
                Informa UK Limited
                0927-3948
                1744-5078
                August 09 2023
                October 28 2022
                August 09 2023
                : 31
                : 7
                : 1362-1385
                Affiliations
                [1 ]Department of Ophthalmology, Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore
                [2 ]Department of Vitreo-retina and Uvea, Sadguru Netra Chikatsalaya, Chitrakoot, India
                [3 ]Department of Vitreo-retina, Anant Bajaj Retina Institute, LV Prasad Eye Institute, Hyderabad, India
                [4 ]Department of Ophthalmology, University of Thessaly, Volos, Greece
                [5 ]Advanced Eye Centre, Post-graduate Institute of Medical Education and Research (PGIMER), Chandigarh, India
                [6 ]Department of Ophthalmology, National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore
                [7 ]Eye ACP programme, Duke NUS Medical School, Singapore
                [8 ]Ocular Infections and AntiMicrobials Group, Singapore Eye Research Institute, Singapore
                Article
                10.1080/09273948.2022.2126863
                36306406
                f9f8be28-aefa-47e0-bdda-177e2210bb9c
                © 2023
                History

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