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SATB1 is Down-regulated in Clear Cell Renal Cell Carcinoma and Correlates with miR-21-5p Overexpression and Poor Prognosis.

Author(s): Anna E. Kowalczyk, Bartlomiej Krazinski, Janusz Godlewski, Jedrzej Grzegrzolka, Jolanta Kiewisz, Przemyslaw Kwiatkowski, Agnieszka Sliwinska-Jewsiewicka, Piotr Dziegiel, Zbigniew Kmieć

Publication date: 2016-04-24

Journal: Cancer genomics & proteomics

Keywords: SATB1 expression, IHC, clear cell renal cell carcinoma, clinicopathological parameters, miR-21-5p, qPCR, survival

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Abstract

Altered expression of special AT-rich sequence binding protein 1 (SATB1) was reported in several types of human cancers. This study aimed to determine the expression levels of SATB1, as well as miR-21-5p -the post-transcriptional repressor of SATB1 expression- in clear cell renal cell carcinoma (ccRCC) and to investigate their association with the progression of ccRCC.

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PubMed ID:: 27107063

Keywords: SATB1 expression,IHC,clear cell renal cell carcinoma,clinicopathological parameters,miR-21-5p,qPCR,survival

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Keywords: SATB1 expression, IHC, clear cell renal cell carcinoma, clinicopathological parameters, miR-21-5p, qPCR, survival

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