Inviting an author to review:
Find an author and click ‘Invite to review selected article’ near their name.
Search for authorsSearch for similar articles
2
views
0
recommends
+1 Recommend
0 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Design and Additive Manufacturing of a Biomimetic Customized Cranial Implant Based on Voronoi Diagram

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          Reconstruction of cranial defects is an arduous task for craniomaxillofacial surgeons. Additive manufacturing (AM) or three-dimensional (3D) printing of titanium patient-specific implants (PSIs) made its way into cranioplasty, improving the clinical outcomes in complex surgical procedures. There has been a significant interest within the medical community in redesigning implants based on natural analogies. This paper proposes a workflow to create a biomimetic patient-specific cranial prosthesis with an interconnected strut macrostructure mimicking bone trabeculae. The method implements an interactive generative design approach based on the Voronoi diagram or tessellations. Furthermore, the quasi-self-supporting fabrication feasibility of the biomimetic, lightweight titanium cranial prosthesis design is assessed using Selective Laser Melting (SLM) technology.

          Related collections

          Most cited references58

          • Record: found
          • Abstract: not found
          • Article: not found

          Ti based biomaterials, the ultimate choice for orthopaedic implants – A review

            Bookmark
            • Record: found
            • Abstract: not found
            • Article: not found

            Iterative point matching for registration of free-form curves and surfaces

              Bookmark
              • Record: found
              • Abstract: found
              • Article: not found

              Laser and electron-beam powder-bed additive manufacturing of metallic implants: A review on processes, materials and designs.

              Additive manufacturing (AM), also commonly known as 3D printing, allows the direct fabrication of functional parts with complex shapes from digital models. In this review, the current progress of two AM processes suitable for metallic orthopaedic implant applications, namely selective laser melting (SLM) and electron beam melting (EBM) are presented. Several critical design factors such as the need for data acquisition for patient-specific design, design dependent porosity for osteo-inductive implants, surface topology of the implants and design for reduction of stress-shielding in implants are discussed. Additive manufactured biomaterials such as 316L stainless steel, titanium-6aluminium-4vanadium (Ti6Al4V) and cobalt-chromium (CoCr) are highlighted. Limitations and future potential of such technologies are also explored.
                Bookmark

                Author and article information

                Contributors
                Journal
                Front Physiol
                Front Physiol
                Front. Physiol.
                Frontiers in Physiology
                Frontiers Media S.A.
                1664-042X
                09 April 2021
                2021
                : 12
                : 647923
                Affiliations
                [1] 1Clinic of Oral and Cranio-Maxillofacial Surgery, University Hospital Basel , Basel, Switzerland
                [2] 2Department of Biomedical Engineering, Medical Additive Manufacturing Research Group (SwissMAM), University of Basel , Allschwil, Switzerland
                [3] 3Department of Oral and Cranio-Maxillofacial Surgery, “Iuliu Hatieganu” University of Medicine and Pharmacy , Cluj-Napoca, Romania
                [4] 4Department of Radiology and Nuclear Medicine, University Hospital Basel , Basel, Switzerland
                Author notes

                Edited by: Chunze Yan, Huazhong University of Science and Technology, China

                Reviewed by: David B. Stout, Independent Researcher, Culver City, CA, United States; Swee Leong Sing, Nanyang Technological University, Singapore

                *Correspondence: Florian Markus Thieringer florian.thieringer@ 123456usb.ch

                This article was submitted to Medical Physics and Imaging, a section of the journal Frontiers in Physiology

                †These authors have contributed equally to this work and share first authorship

                Article
                10.3389/fphys.2021.647923
                8063040
                33897455
                05223e6e-2795-4fa9-a2f6-acc418d88fc7
                Copyright © 2021 Sharma, Ostas, Rotar, Brantner and Thieringer.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 30 December 2020
                : 15 March 2021
                Page count
                Figures: 9, Tables: 0, Equations: 0, References: 58, Pages: 12, Words: 7515
                Categories
                Physiology
                Original Research

                Anatomy & Physiology
                biomimetics,computer-aided design,cranial reconstruction,patient-specific implant,selective laser melting,voronoi diagram,additive manufacturing,3d printing

                Comments

                Comment on this article