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      Retrospective assessment of a collaborative digital asthma program for Medicaid-enrolled children in southwest Detroit: reductions in short-acting beta-agonist (SABA) medication use

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          Abstract

          Background

          Real-world evidence for digitally-supported asthma programs among Medicaid-enrolled children remains limited. Using data from a collaborative quality improvement program, we evaluated the impact of a digital intervention on asthma inhaler use among children in southwest Detroit.

          Methods

          Children (6–13 years) enrolled with Kids Health Connection (KHC), a program involving home visits with an asthma educator, were invited to participate in a digital self-management asthma program (Propeller Health). Patients were provided with a sensor to capture short-acting beta-agonist (SABA) medication use, and given access to a paired mobile app to track usage. Patients’ healthcare providers and caregivers (“followers”) were invited to view data as well. Retrospective paired t-tests assessed change in mean SABA use and SABA-free days (SFD) over time, and regressions explored the relationship between followers and medication use.

          Results

          Fifty-one patients were assessed. Mean program participation was nine months, and patients had on average 3 followers. From the first to last participation month, mean SABA use decreased from 0.68 to 0.25 puffs/day ( p < 0.001), and mean SFD increased from 25.2 to 28.1 days/month ( p < 0.001). 76% of patients had an increase in the number of SFD. There was a positive, but non-significant, relationship between the number of followers and reductions in SABA inhaler use.

          Conclusions

          We observed a significant reduction in SABA inhaler use and an increase in the number of SABA-free days among Medicaid-enrolled children enrolled in a multi-modal digital asthma program.

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          Most cited references15

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          Systematic review of the Hawthorne effect: New concepts are needed to study research participation effects☆

          Objectives This study aims to (1) elucidate whether the Hawthorne effect exists, (2) explore under what conditions, and (3) estimate the size of any such effect. Study Design and Setting This systematic review summarizes and evaluates the strength of available evidence on the Hawthorne effect. An inclusive definition of any form of research artifact on behavior using this label, and without cointerventions, was adopted. Results Nineteen purposively designed studies were included, providing quantitative data on the size of the effect in eight randomized controlled trials, five quasiexperimental studies, and six observational evaluations of reporting on one's behavior by answering questions or being directly observed and being aware of being studied. Although all but one study was undertaken within health sciences, study methods, contexts, and findings were highly heterogeneous. Most studies reported some evidence of an effect, although significant biases are judged likely because of the complexity of the evaluation object. Conclusion Consequences of research participation for behaviors being investigated do exist, although little can be securely known about the conditions under which they operate, their mechanisms of effects, or their magnitudes. New concepts are needed to guide empirical studies.
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            Development of the asthma control test: a survey for assessing asthma control.

            Asthma guidelines indicate that the goal of treatment should be optimum asthma control. In a busy clinic practice with limited time and resources, there is need for a simple method for assessing asthma control with or without lung function testing. The objective of this article was to describe the development of the Asthma Control Test (ACT), a patient-based tool for identifying patients with poorly controlled asthma. A 22-item survey was administered to 471 patients with asthma in the offices of asthma specialists. The specialist's rating of asthma control after spirometry was also collected. Stepwise regression methods were used to select a subset of items that showed the greatest discriminant validity in relation to the specialist's rating of asthma control. Internal consistency reliability was computed, and discriminant validity tests were conducted for ACT scale scores. The performance of ACT was investigated by using logistic regression methods and receiver operating characteristic analyses. Five items were selected from regression analyses. The internal consistency reliability of the 5-item ACT scale was 0.84. ACT scale scores discriminated between groups of patients differing in the specialist's rating of asthma control (F = 34.5, P <.00001), the need for change in patient's therapy (F = 40.3, P <.00001), and percent predicted FEV(1) (F = 4.3, P =.0052). As a screening tool, the overall agreement between ACT and the specialist's rating ranged from 71% to 78% depending on the cut points used, and the area under the receiver operating characteristic curve was 0.77. Results reinforce the usefulness of a brief, easy to administer, patient-based index of asthma control.
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              Regression to the mean: what it is and how to deal with it.

              A Barnett (2004)
              Regression to the mean (RTM) is a statistical phenomenon that can make natural variation in repeated data look like real change. It happens when unusually large or small measurements tend to be followed by measurements that are closer to the mean. We give some examples of the phenomenon, and discuss methods to overcome it at the design and analysis stages of a study. The effect of RTM in a sample becomes more noticeable with increasing measurement error and when follow-up measurements are only examined on a sub-sample selected using a baseline value. RTM is a ubiquitous phenomenon in repeated data and should always be considered as a possible cause of an observed change. Its effect can be alleviated through better study design and use of suitable statistical methods.
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                Author and article information

                Contributors
                meredith.barrett@resmed.com
                rahgonda@gmail.com
                vy.vuong@resmed.com
                leanne.kaye@resmed.com
                alexbhill@wayne.edu
                elliottattisha@gmail.com
                tholtrop@wchap.org
                Journal
                Asthma Res Pract
                Asthma Res Pract
                Asthma Research and Practice
                BioMed Central (London )
                2054-7064
                20 May 2023
                20 May 2023
                2023
                : 9
                : 3
                Affiliations
                [1 ]ResMed Science Center, San Diego, USA
                [2 ]GRID grid.418848.9, ISNI 0000 0004 0458 4007, IQVIA; Formerly ResMed Science Center, ; Durham, USA
                [3 ]GRID grid.254444.7, ISNI 0000 0001 1456 7807, Department of Urban Studies and Planning, , Wayne State University; formerly Detroit Health Department, ; Detroit, USA
                [4 ]Formerly Detroit Public Schools Community District, Detroit, USA
                [5 ]Wayne Children’s Healthcare Access Program, Inc, Dba Kids’ Health Connections, Detroit, USA
                Author information
                http://orcid.org/0000-0002-5345-7026
                Article
                92
                10.1186/s40733-023-00092-0
                10199538
                37210572
                05da1ad4-b918-4f34-8016-40fcff411fe3
                © The Author(s) 2023

                Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

                History
                : 23 March 2023
                : 15 May 2023
                Funding
                Funded by: Skillman Foundation
                Funded by: FundRef http://dx.doi.org/10.13039/100020493, Propeller Health;
                Funded by: FundRef http://dx.doi.org/10.13039/100017647, ResMed;
                Categories
                Research
                Custom metadata
                © BioMed Central Ltd. 2023

                asthma,short-acting beta-agonist,saba,digital health,electronic monitoring,sensor,medicaid,pediatric

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