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Cutaneous squamous cell carcinoma
February 2018
February 2018
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Abstract
Cutaneous squamous cell carcinoma (cSCC), a malignant proliferation of cutaneous epithelium,
represents 20% to 50% of skin cancers. Although the majority of cSCCs are successfully
eradicated by surgical excision, a subset of cSCC possesses features associated with
a higher likelihood of recurrence, metastasis, and death. The proper identification
of these aggressive cSCCs can guide additional work-up and management. In the first
article in this continuing medical education series, we discuss the incidence, recurrence
rates, mortality rates, and risk factors associated with cSCC and review the staging
systems used to stratify patients into high- and low-risk groups. The second article
in this series reviews the treatment options for cSCC, with focused attention on the
management of high-stage tumors.