Transcription and processing of human microRNA precursors.

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Abstract

MicroRNAs have recently emerged as key posttranscriptional regulators of eukaryotic gene expression, yet our understanding of how microRNA expression is itself controlled has remained rudimentary. This review describes recent insights into the mechanisms governing microRNA transcription and processing in vertebrates and their implications for understanding the regulation of microRNA biogenesis.

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Journal

Journal ID (iso-abbrev): Mol Cell

Title: Molecular cell

Publisher: Elsevier BV

ISSN: 1097-2765

ISSN (Print): 1097-2765

Publication date (Electronic): Dec 22 2004

Volume: 16

Issue: 6

Affiliations

[1 ] Howard Hughes Medical Institute and Department of Molecular Genetics and Microbiology, Duke University Medical Center, Durham, NC 27710, USA. culle002@mc.duke.edu

Article

Publisher Item ID: S1097-2765(04)00756-7

DOI: 10.1016/j.molcel.2004.12.002

PubMed ID: 15610730

SO-VID: 2dc76f9b-e733-48d5-8c58-66e3260f4ac9

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