Safety and Feasibility of Intrastromal Injection of Cultivated Human Corneal Stromal Keratocytes as Cell-Based Therapy for Corneal Opacities.

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Abstract

To evaluate the safety and feasibility of intrastromal injection of human corneal stromal keratocytes (CSKs) and its therapeutic effect on a rodent early corneal opacity model.

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Journal

Journal ID (iso-abbrev): Invest. Ophthalmol. Vis. Sci.

Title: Investigative ophthalmology & visual science

Publisher: Association for Research in Vision and Ophthalmology (ARVO)

ISSN (Electronic): 1552-5783

ISSN (Print): 0146-0404

Publication date (Electronic): Jul 02 2018

Volume: 59

Issue: 8

Affiliations

[1 ] Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, Singapore.

[2 ] Eye-Academic Clinical Program, Duke-National University Singapore Graduate Medical School, Singapore.

[3 ] Department of Ophthalmology, Rheinisch-Westfälische Technische Hochschule (RWTH) Aachen University, Aachen, Germany.

[4 ] Singapore National Eye Centre, Singapore.

[5 ] School of Material Science and Engineering, Nanyang Technological University, Singapore.

Article

Publisher Item ID: 2687658

DOI: 10.1167/iovs.17-23575

PubMed ID: 30025076

SO-VID: 520c3be5-c8d0-4728-af23-c9f1385dfe33

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