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      The Relationship between Air Pollution and Infant Mortality Rate

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          Abstract

          Background:

          We aimed to investigate the relationship between air pollution and the Infant mortality rate (IMR) during nearly ten years in Tehran, Iran.

          Methods:

          This study is a retrospective cohort case using time series analysis. Air pollution monitoring data during the study period (2009–2018) were collected from the information of 23 Air Quality Control Centers in different areas of Tehran. For this purpose, the daily measures of PM10, PM2.5, O3, CO, SO2, NO2 were obtained. Data on infant mortality was obtained from the National Statistics Office of Iran and mortality registered in Tehran’s main cemetery during the study period. Distributed lag linear and non-linear models were used.

          Results:

          A total of 23,206 infant deaths were reported during the study period. Following an increase of 10 ug/m3 in PM10 in an early day of exposure, the risk of mortality increased significantly (RR=1.003, 95%CI:1.001–1.005). There is a pick on lag 5–10 that shows a very strong and immediate effect of cold temperature which means that cold temperatures increase the risk of mortality at an early time. At cold temperate, (var=0 and lag 0) risk of infant mortality was significantly higher than reference temperature (19°C) (RR=1.1295, %CI: 1.01–1.25).

          Conclusion:

          The results show the adverse effects of PM10 exposure on infant mortality in Tehran, Iran. Accordingly, a steady decline in PM10 levels in Tehran may have greater benefits in reducing the Infant mortality rate.

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          Most cited references48

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          Human health effects of air pollution.

          Hazardous chemicals escape to the environment by a number of natural and/or anthropogenic activities and may cause adverse effects on human health and the environment. Increased combustion of fossil fuels in the last century is responsible for the progressive change in the atmospheric composition. Air pollutants, such as carbon monoxide (CO), sulfur dioxide (SO(2)), nitrogen oxides (NOx), volatile organic compounds (VOCs), ozone (O(3)), heavy metals, and respirable particulate matter (PM2.5 and PM10), differ in their chemical composition, reaction properties, emission, time of disintegration and ability to diffuse in long or short distances. Air pollution has both acute and chronic effects on human health, affecting a number of different systems and organs. It ranges from minor upper respiratory irritation to chronic respiratory and heart disease, lung cancer, acute respiratory infections in children and chronic bronchitis in adults, aggravating pre-existing heart and lung disease, or asthmatic attacks. In addition, short- and long-term exposures have also been linked with premature mortality and reduced life expectancy. These effects of air pollutants on human health and their mechanism of action are briefly discussed.
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            Distributed lag non-linear models

            Environmental stressors often show effects that are delayed in time, requiring the use of statistical models that are flexible enough to describe the additional time dimension of the exposure–response relationship. Here we develop the family of distributed lag non-linear models (DLNM), a modelling framework that can simultaneously represent non-linear exposure–response dependencies and delayed effects. This methodology is based on the definition of a ‘cross-basis’, a bi-dimensional space of functions that describes simultaneously the shape of the relationship along both the space of the predictor and the lag dimension of its occurrence. In this way the approach provides a unified framework for a range of models that have previously been used in this setting, and new more flexible variants. This family of models is implemented in the package dlnm within the statistical environment R. To illustrate the methodology we use examples of DLNMs to represent the relationship between temperature and mortality, using data from the National Morbidity, Mortality, and Air Pollution Study (NMMAPS) for New York during the period 1987–2000. Copyright © 2010 John Wiley & Sons, Ltd.
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              Socioeconomic disparities in adverse birth outcomes: a systematic review.

              Adverse birth outcomes, such as preterm birth and low birth weight, have serious health consequences across the life course. Socioeconomic disparities in birth outcomes have not been the subject of a recent systematic review. The aim of this study was to systematically review the literature on the association of socioeconomic disadvantage with adverse birth outcomes, with specific attention to the strength and consistency of effects across socioeconomic measures, birth outcomes, and populations. Relevant articles published from 1999 to 2007 were obtained through electronic database searches and manual searches of reference lists. English-language studies from industrialized countries were included if (1) study objectives included examination of a socioeconomic disparity in a birth outcome and (2) results were presented on the association between a socioeconomic predictor and a birth outcome related to birth weight, gestational age, or intrauterine growth. Two reviewers extracted data and independently rated study quality; data were analyzed in 2008-2009. Ninety-three of 106 studies reported a significant association, overall or within a population subgroup, between a socioeconomic measure and a birth outcome. Socioeconomic disadvantage was consistently associated with increased risk across socioeconomic measures, birth outcomes, and countries; many studies observed racial/ethnic differences in the effect of socioeconomic measures. Socioeconomic differences in birth outcomes remain pervasive, with substantial variation by racial or ethnic subgroup, and are associated with disadvantage measured at multiple levels (individual/family, neighborhood) and time points (childhood, adulthood), and with adverse health behaviors that are themselves socially patterned. Future reviews should focus on identifying interventions to successfully reduce socioeconomic disparities in birth outcomes. 2010 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.
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                Author and article information

                Journal
                Iran J Public Health
                Iran J Public Health
                IJPH
                Iranian Journal of Public Health
                Tehran University of Medical Sciences
                2251-6085
                2251-6093
                June 2023
                : 52
                : 6
                : 1278-1288
                Affiliations
                [1. ]Department of Midwifery, Faculty of Medical Sciences, Varamin-Pishva Branch, Islamic Azad University, Tehran, Iran
                [2. ]Department of Chemical Engineering, Health, Safety & Environment, Najafabad Branch, Islamic Azad University, Najafabad, Iran
                [3. ]Midwifery and Reproductive Health Research Center, Department of Midwifery and Reproductive Health, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran
                [4. ]Department of Biostatistics, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
                Author notes
                [* ] Corresponding Author: Email: msimbar@ 123456gmail.com
                Article
                IJPH-52-1278
                10.18502/ijph.v52i6.12994
                10362819
                63ce2825-7bcf-46ad-95b6-d7e2754e21aa
                Copyright © 2023 Nazarpour et al. Published by Tehran University of Medical Sciences

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license ( https://creativecommons.org/licenses/by-nc/4.0/). Non-commercial uses of the work are permitted, provided the original work is properly cited.

                History
                : 11 January 2022
                : 05 April 2022
                Categories
                Original Article

                Public health
                air pollution,infant mortality rate,time series
                Public health
                air pollution, infant mortality rate, time series

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