Intravenous immunoglobulin G modulates peripheral blood Th17 and Foxp3(+) regulatory T cells in pregnant women with recurrent pregnancy loss.

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Abstract

Th17 cells and Foxp3(+) regulatory T (Treg) cells have been proposed as new risk factors for recurrent pregnancy loss (RPL). Intravenous immunoglobulin G (IVIG) was reported to modulate various immune cells. In this study, we investigated the effect of IVIG on the levels of Th17 and Treg cells and pregnancy outcome in women with RPL.

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Journal

Journal ID (iso-abbrev): Am. J. Reprod. Immunol.

Title: American journal of reproductive immunology (New York, N.Y. : 1989)

ISSN (Electronic): 1600-0897

ISSN (Print): 1046-7408

Publication date (Electronic): May 2014

Volume: 71

Issue: 5

Affiliations

[1 ] Department of Obstetrics and Gynecology, College of Medicine, Konyang University, Seo-gu, Daejeon, Korea.

Article

DOI: 10.1111/aji.12208

PubMed ID: 24645850

SO-VID: 7d3f0a7e-7da9-483c-85f7-b9e384db46b8

History

Keywords: IL-17,Th17 cells,intravenous immunoglobulin,recurrent pregnancy loss,regulatory T cells

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Keywords: IL-17, Th17 cells, intravenous immunoglobulin, recurrent pregnancy loss, regulatory T cells

Intravenous immunoglobulin G modulates peripheral blood Th17 and Foxp3(+) regulatory T cells in pregnant women with recurrent pregnancy loss.

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Abstract

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Regulatory T cell (Treg) therapy

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